Peptide ELISA: 1/64000. Western Blot: 0.1 - 0.3 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
GCNT3 is a glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. GCNT3 mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. GCNT3 has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development. GCNT3 belongs to the glycosyltransferase 14 family.Synonyms: 3-galactosyl-O-glycosyl-glycoprotein beta-1, 6-N-acetylglucosaminyltransferase, 6-N-acetylglucosaminyltransferase 3, Beta-1, C2/4GnT, C2GnT-mucin type, Core 2/core 4 beta-1