MC2R 抗体 (N-Term)
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- 抗原 See all MC2R 抗体
- MC2R (Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This MC2R antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody reacts to MC2R / ACTHR.
- 纯化方法
- Affinity chromatography
- 免疫原
- Peptide with sequence ENINNTARNNSDC, from the N Terminus of the protein sequence
- Top Product
- Discover our top product MC2R Primary Antibody
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anti-Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R) (AA 261-288) antibody
MC2R 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22805 unconjugated
anti-Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R) (C-Term) antibodyMC2R 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R) (C-Term) antibodyMC2R 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R) (N-Term) antibodyMC2R 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R) (N-Term) antibodyVerified MC2R 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R) (AA 86-135) antibodyMC2R 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R) (AA 248-297) antibodyMC2R 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R) (1st Extracellular Loop), (AA 87-99) antibodyMC2R 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Peptide ELISA: 1/32000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0,5 mg/mL
- 缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- MC2R (Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R))
- 别名
- MC2-R (MC2R 产品)
- 别名
- ACTHR antibody, ACTH-R antibody, MC2-R antibody, MC2R antibody, MC2 antibody, melanocortin 2 receptor antibody, MC2R antibody, Mc2r antibody, mc2r antibody
- 背景
- MC2 receptor is the second member of the five known melanocortin receptors (MCRs) belonging to the rhodopsin-like family of G protein-coupled receptors (GPCRs). These five MCRs form a unique family of GPCRs, marked by their unusually short coding sequence and the absence of highly conserved amino acid residues or motifs common to most GPCRs. All MCRs signal through the cyclic adenosine 3', 5'-monophosphate (cAMP) pathway. MC2 receptor is the smallest MCR and the smallest known GPCR (297 amino acids). It exclusively binds the adrenocorticotrophic hormone (ACTH) and this binding plays a pivotal role in homeostasis, metabolism, and stress response. In contrast, the other four MCRs are activated by both ACTH and melanocyte-stimulating hormones (MSHs and mainly alpha-MSH). The MC2 receptor is predominantly expressed in the adrenal gland but is also found in the murine adipocyte. Mutations in MC2R can result in familial glucocorticoid deficiency.Synonyms: ACTH receptor, ACTH-R, ACTHR, Adrenocorticotropic hormone receptor, Adrenocorticotropin receptor, MC2R
- 基因ID
- 4158, 9606
- UniProt
- Q01718
- 途径
- cAMP Metabolic Process
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