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NR0B1 抗体 (Internal Region)

NR0B1 适用: 人 WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374822
发货至: 中国
  • 抗原 See all NR0B1 抗体
    NR0B1 (Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1))
    抗原表位
    • 13
    • 13
    • 8
    • 8
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 89
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 80
    • 10
    • 1
    山羊
    克隆类型
    • 75
    • 16
    多克隆
    标记
    • 49
    • 8
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This NR0B1 antibody is un-conjugated
    应用范围
    • 68
    • 44
    • 27
    • 11
    • 9
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody reacts to DAX1 / NR0B1.
    纯化方法
    Affinity chromatography
    免疫原
    Peptide with sequence CGEDHPQQGSTLY, from the internal region of the protein sequence
    Top Product
    Discover our top product NR0B1 Primary Antibody
  • 应用备注
    Peptide ELISA: 1/32000. Western Blot: 0.5 - 1.5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0,5 mg/mL
    缓冲液
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    NR0B1 (Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1))
    别名
    NR0B1 (NR0B1 产品)
    别名
    DAX antibody, NR0B1 antibody, dax1 antibody, AHC antibody, AHCH antibody, AHX antibody, DAX-1 antibody, DAX1 antibody, DSS antibody, GTD antibody, HHG antibody, NROB1 antibody, SRXY2 antibody, Ahc antibody, Ahch antibody, Dax1 antibody, nuclear receptor subfamily 0 group B member 1 antibody, nuclear receptor subfamily 0, group B, member 1 antibody, nuclear receptor subfamily 0 group B member 1 L homeolog antibody, NR0B1 antibody, nr0b1 antibody, nr0b1.L antibody, Nr0b1 antibody
    背景
    NR0B1 is a receptor that may be a component of a cascade required for development of steroidogenic tissues. It acts as a dominant negative regulator of transcription mediated by the retinoic acid receptor. It interacts with COPS2. Defects in NR0B1 are the cause of X-linked adrenal hypoplasia congenital (AHC). AHC is a developmental disorder of the adrenal gland that results in profound hormonal deficiencies and is lethal if untreated. It is characterized by the absence of the permanent zone of the adrenal cortex and by a structural disorganization of the glands. Hypogonadotropic hypogonadism (HHG) is frequently associated with this disorder. HHG is a condition resulting from or characterized by abnormally decreased gonadal function, with retardation of growth and sexual development.Synonyms: AHC, DAX1, DSS-AHC critical region on the X chromosome protein 1, Nuclear receptor DAX-1, Nuclear receptor subfamily 0 group B member 1
    基因ID
    190
    NCBI登录号
    NP_000466
    UniProt
    P51843
    途径
    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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