PICK1 抗体 (Internal Region)
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- 抗原 See all PICK1 抗体
- PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠, 犬, Pig
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This PICK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody reacts to PICK1.
- 交叉反应 （详细）
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Species reactivity (expected):Human, Canine, Pig.
Species reactivity (tested):Mouse, Rat. - 纯化方法
- Affinity chromatography
- 免疫原
- Peptide with sequence C-HYNKLQADPKQ, from the internal region of the protein sequence .Remarks: Reported variants represent identical protein (NP_036539.1, NP_001034672.1, NP_001034673.1).
- Top Product
- Discover our top product PICK1 Primary Antibody
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anti-Protein Interacting With Protein Kinase C, alpha 1 (PICK1) antibody
PICK1 适用: 人 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 1-200) antibodyPICK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 266-375) antibodyPICK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G5 unconjugated
anti-Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (Internal Region) antibodyVerified PICK1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 24-229) antibodyPICK1 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (C-Term) antibodyPICK1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (N-Term) antibodyPICK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 260-360) antibodyPICK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 305-318), (alpha-helix Domain), (Intracellular) antibodyPICK1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 266-375) antibodyPICK1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))
- 别名
- PICK1 (PICK1 产品)
- 别名
- PICK antibody, PRKCABP antibody, Prkcabp antibody, prkcabp antibody, MGC131295 antibody, PICK1 antibody, DKFZp470L2127 antibody, protein interacting with PRKCA 1 antibody, protein interacting with C kinase 1 antibody, protein interacting with PRKCA 1 L homeolog antibody, PICK1 antibody, Pick1 antibody, pick1 antibody, pick1.L antibody
- 背景
- PSD-95/DLG/ZO-1 (PDZ) domain containing proteins play a central role in synaptic membrane protein localization. The protein interacting with protein kinase C (PICK 1) is a synaptic PDZ domain protein that also contains a coiled-coil and acidic domain. Studies indicate that PICK 1 functions as a targeting and transport protein and has been shown to interact with protein kinase C alpha (PKC alpha), AMPA type glutamate receptors, and several other membrane receptors via its PDZ domain. The interaction of PICK 1 with PKC alpha is highly dependent on the activation of the kinase. It appears that PICK 1 directs the activated form of PKC alpha to membrane anchored GluR2. Once phosphorylated by PKC alpha, GluR2 is released from the synaptic anchor proteins. Once released, GluR2 is transported from the synaptic membrane in a PICK 1 dependent manner.Synonyms: PRKCA-binding protein, PRKCABP, Protein interacting with C kinase 1, Protein kinase C-alpha-binding protein
- 基因ID
- 9463
- NCBI登录号
- NP_001034672
- UniProt
- Q9NRD5
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