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NONO 抗体 (C-Term)

NONO 适用: 人, 小鼠, 大鼠, 犬 WB, IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374683
发货至: 中国
  • 抗原 See all NONO 抗体
    NONO (Non-POU Domain Containing, Octamer-Binding (NONO))
    抗原表位
    • 15
    • 12
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    C-Term
    适用
    • 76
    • 36
    • 32
    • 15
    • 10
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 70
    • 5
    • 2
    山羊
    克隆类型
    • 62
    • 15
    多克隆
    标记
    • 37
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This NONO antibody is un-conjugated
    应用范围
    • 59
    • 35
    • 27
    • 17
    • 14
    • 14
    • 14
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    序列
    C-NRAAPGAEFA PNK
    特异性
    This antibody recognizes NONO / NMT55.
    交叉反应 (详细)
    Species reactivity (expected):Rat, Canine.
    Species reactivity (tested):Human, Mouse.
    纯化方法
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Peptide with sequence from the C Terminus of the protein sequence (NP_031389.3). Genename: NONO
    Top Product
    Discover our top product NONO Primary Antibody
  • 应用备注
    Peptide ELISA: 1/16000. Western Blot: 0.1 - 0.3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3 with 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    NONO (Non-POU Domain Containing, Octamer-Binding (NONO))
    别名
    NONO / NMT55 (NONO 产品)
    别名
    NMT55 antibody, NRB54 antibody, P54 antibody, P54NRB antibody, nmt55 antibody, nrb54 antibody, p54nrb antibody, xp54nrb antibody, AA407051 antibody, AV149256 antibody, nonA antibody, non-POU domain containing octamer binding antibody, non-POU domain containing, octamer-binding antibody, non-POU domain containing, octamer binding L homeolog antibody, non-POU-domain-containing, octamer binding protein antibody, NONO antibody, Nono antibody, nono.L antibody
    背景
    Nmt55/p54nrb is a DNA and RNA binding protein that has been implicated in multiple cellular functions such as regulation of cell division as well as cancer biology. Expression of this protein has been found to be decreased in some human breast tumors, and has been studied as a relevant tumor marker. It has been found that decreased nmt55/p54nrb expression in Estrogen Receptor (ER)-negative human breast tumors or the expression of nmt55/p54nrb variants in ER-positive tumors may indicate the loss of normal growth. It is possible that nmt55/p54nrb acts as a pre-mRNA splicing factor affecting the structure and function of hERalpha.Synonyms: NRB54
    基因ID
    4841
    NCBI登录号
    NP_001138880
    UniProt
    Q15233
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