BID 抗体 (C-Term)
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Quick Overview for BID 抗体 (C-Term) (ABIN374543)
抗原
See all BID 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- C-TYVRSLARNG MD
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特异性
- This antibody reacts to BH3-interacting domain death agonist. It is expected to recognise all three reported isoforms (as represented by NP_932070.1, NP_001187.1, NP_932071.1)
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity Chromatography
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免疫原
- Peptide with sequence from the C Terminus of the protein sequence according to NP_932070.1, NP_001187.1, NP_932071.1. Genename: BID
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anti-BH3 Interacting Domain Death Agonist (BID) (AA 68-103) antibody
BID 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB0957-RB0958 unconjugated
anti-BH3 Interacting Domain Death Agonist (BID) (AA 1-195) antibodyBID 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-BH3 Interacting Domain Death Agonist (BID) antibodyBID 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3C5 unconjugated
anti-BH3 Interacting Domain Death Agonist (BID) (AA 1-196) antibodyBID 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-BH3 Interacting Domain Death Agonist (BID) (AA 1-130) antibodyBID 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-BH3 Interacting Domain Death Agonist (BID) (AA 1-195) antibodyBID 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-BH3 Interacting Domain Death Agonist (BID) (AA 68-103) antibodyBID 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BH3 Interacting Domain Death Agonist (BID) (AA 1-195) antibodyBID 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-BH3 Interacting Domain Death Agonist (BID) (AA 1-195) antibodyBID 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 3F3-1A3 unconjugated
anti-BH3 Interacting Domain Death Agonist (BID) (AA 1-195) antibodyBID 适用: 人 WB, IHC, IF, ICC, FACS 宿主: 小鼠 Monoclonal 10F4 unconjugated
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应用备注
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Peptide ELISA: 1/8000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3 containing 0.02 % Sodium Azide and 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- BID (BH3 Interacting Domain Death Agonist (BID))
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别名
- BID
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背景
- Bid, a BH3 domain containing proapoptotic Bcl2 family member, is localized in the cytosolic fraction of cells as an inactive precursor. Its active form is generated upon proteolytic cleavage by caspase 8 in the Fas signaling pathway. Cleaved Bid translocates to mitochondria and releases its potent proapoptotic activity, which in turn induces cytochrome c release and mitochondrial damage. The cytochrome c releasing activity of Bid was antagonized by Bcl2. Mutation in the SH3 domain can diminish the cytochrome c releasing activity. In animal model studies, Bid deficient mice are found resistant to the lethal effects of death factor signals relayed through Fas.Synonyms: BH3-interacting domain death agonist, p22 BID
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分子量
- 26.8kDa (NP_932070.1) and 22.0kDa (NP_001187.1).
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基因ID
- 637, 9606
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UniProt
- P55957
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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