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Neuroserpin 抗体 (C-Term)

SERPINI1 适用: 人, 小鼠, 大鼠, Chimpanzee WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374537
发货至: 中国
  • 抗原 See all Neuroserpin (SERPINI1) 抗体
    Neuroserpin (SERPINI1) (serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1))
    抗原表位
    • 15
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 54
    • 19
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Chimpanzee
    宿主
    • 49
    • 4
    • 3
    • 1
    • 1
    山羊
    克隆类型
    • 54
    • 4
    多克隆
    标记
    • 21
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Neuroserpin antibody is un-conjugated
    应用范围
    • 46
    • 27
    • 17
    • 14
    • 13
    • 13
    • 12
    • 8
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody reacts to Neuroserpin.
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat, Bovine.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    免疫原
    Peptide with sequence C-TMNTSGHDFEEL, from the C Terminus of the protein sequence
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    Discover our top product SERPINI1 Primary Antibody
  • 应用备注
    Peptide ELISA: 1/32000. Western Blot: 1 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0,5 mg/mL
    缓冲液
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Neuroserpin (SERPINI1) (serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1))
    别名
    Neuroserpin / SERPINI1 (SERPINI1 产品)
    别名
    PI12 antibody, neuroserpin antibody, AI837402 antibody, Ns antibody, PI-12 antibody, Spi17 antibody, CG9453 antibody, Dmel\\CG9453 antibody, Serp2 antibody, Sp4 antibody, Spn4 antibody, Spn4A antibody, dSerp2 antibody, sp4 antibody, spn4 antibody, raPIT5a antibody, SERPINI1 antibody, pi12 antibody, serpini1l antibody, si:ch211-167c22.4 antibody, serpin family I member 1 antibody, serine (or cysteine) peptidase inhibitor, clade I, member 1 antibody, Serpin 42Da antibody, serpin peptidase inhibitor, clade I (neuroserpin), member 1 antibody, serpin family I member 1 L homeolog antibody, SERPINI1 antibody, Serpini1 antibody, Spn42Da antibody, serpini1 antibody, serpini1.L antibody
    背景
    Neuroserpin is a member of the serpin superfamily and is predominantly expressed by neurons of the developing and adult brain. This serpin is secreted from axonal growth cones of the CNS and PNS where it inhibits the enzyme tissue plasminogen activator. The expression pattern of neuroserpin and its in vivo inhibitory activity implicate this serpin in regulating axonal growth, reducing seizure activity, controlling damage in cerebral infarction and regulating emotional behaviour and memory. Four different mutations have been described in the human neuroserpin gene that promote neuroserpin abnormal polymerization, giving rise to intraneuronal inclusion bodies and a new form of dementia called Familial Encephalopathy with Neuroserpin Inclusion Bodies.Synonyms: PI-12, PI12, Peptidase inhibitor 12, Serpin I1
    基因ID
    5274, 9606
    UniProt
    Q99574
    途径
    Regulation of Hormone Metabolic Process
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