HSD11B1 抗体 (C-Term)
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- 抗原 See all HSD11B1 抗体
- HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
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抗原表位
- C-Term
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适用
- 人, 绵羊, Cow, Chimpanzee
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This HSD11B1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- CTSYNMDRFI NK
- 特异性
- This antibody is expected to recognise Human HSD11B1 protein. Both NP_005516.1 and NP_861420.1 variants encode the same protein.
- 交叉反应 (详细)
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Species reactivity (expected):Bovine.
Species reactivity (tested):Human. - 纯化方法
- Affinity Chromatography
- 免疫原
- Peptide with sequence from the C-Terminus of Human HSD11B1 (NP_005516.1, NP_861420.1) Genename: HSD11B1
- Top Product
- Discover our top product HSD11B1 Primary Antibody
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- 应用备注
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Peptide ELISA: 1/4000. Western Blot: 0.3 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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Inhibition of Lysyl Oxidase by Cortisol Regeneration in Human Amnion: Implications for Rupture of Fetal Membranes." in: Endocrinology, Vol. 157, Issue 10, pp. 4055-4065, (2017) (PubMed).
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Inhibition of Lysyl Oxidase by Cortisol Regeneration in Human Amnion: Implications for Rupture of Fetal Membranes." in: Endocrinology, Vol. 157, Issue 10, pp. 4055-4065, (2017) (PubMed).
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- 抗原
- HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
- 别名
- 11-beta HSD1 / HSD11B1 (HSD11B1 产品)
- 别名
- 11-DH antibody, 11-beta-HSD1 antibody, CORTRD2 antibody, HDL antibody, HSD11 antibody, HSD11B antibody, HSD11L antibody, SDR26C1 antibody, hsd11 antibody, hsd11b antibody, LRRGT00065 antibody, hydroxysteroid 11-beta dehydrogenase 1 antibody, hydroxysteroid (11-beta) dehydrogenase 1b antibody, hydroxysteroid (11-beta) dehydrogenase 1 L homeolog antibody, HSD11B1 antibody, HSD11B1b antibody, hsd11b1.L antibody, Hsd11b1 antibody
- 背景
- HSD11B1 is a microsomal enzyme that catalyses the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyse the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene.Synonyms: 11-DH, 11-beta-hydroxysteroid dehydrogenase 1, Corticosteroid 11-beta-dehydrogenase isozyme 1, HSD11, HSD11L
- 基因ID
- 3290
- NCBI登录号
- NP_001193670
- UniProt
- P28845
- 途径
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Carbohydrate Metabolic Process
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