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COMT 抗体 (N-Term)

COMT 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374503
发货至: 中国
  • 抗原 See all COMT 抗体
    COMT (Catechol-O-Methyltransferase (COMT))
    抗原表位
    • 15
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 58
    • 38
    • 36
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 68
    • 7
    • 3
    • 1
    山羊
    克隆类型
    • 65
    • 14
    多克隆
    标记
    • 47
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This COMT antibody is un-conjugated
    应用范围
    • 41
    • 23
    • 17
    • 13
    • 13
    • 13
    • 9
    • 8
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    特异性
    This antibody is expected to recognise both reported isoforms. Variants (NP_000745.1, NP_001128633.1 and NP_001128634.1) encode the same isoform.
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat and Canine (Dog).
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Peptide with sequence GDTKEQRILNHVLQC, from the N-Terminus of the protein sequence
    Top Product
    Discover our top product COMT Primary Antibody
  • 应用备注
    Peptide ELISA: Detection Limit Dilution: 1/4000. Western Blot: 0.3-1.0 μg/mL. Approx 26 kDa plus 26 kDa bands observed in Human Testislysates (calculated MW of 30.6 kDa according to NP_000745.1 and of 24.6 kDa according toNP_009294.1).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    COMT (Catechol-O-Methyltransferase (COMT))
    别名
    COMT (COMT 产品)
    别名
    Comt1 antibody, D16Wsu103e antibody, D330014B15Rik antibody, COMT antibody, mb-comt antibody, s-comt antibody, comt antibody, MGC154444 antibody, zgc:114157 antibody, si:dkey-13a21.15 antibody, zK13A21.15 antibody, zgc:162236 antibody, catechol-O-methyltransferase antibody, microRNA 4761 antibody, catechol-O-methyltransferase S homeolog antibody, methyltransferase antibody, catechol-o-methyltransferase antibody, catechol-O-methyltransferase a antibody, catechol-O-methyltransferase b antibody, catechol O-methyltransferase antibody, COMT antibody, Comt antibody, MIR4761 antibody, comt antibody, comt.2 antibody, comt.S antibody, Rv1703c antibody, Mb1729c antibody, comta antibody, comtb antibody, LOC100354142 antibody
    背景
    Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease.Synonyms: Catechol O-methyltransferase
    基因ID
    1312, 9606
    UniProt
    P21964
    途径
    Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome
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