VDAC2 抗体 (C-Term)
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- 抗原 See all VDAC2 抗体
- VDAC2 (Voltage-Dependent Anion Channel 2 (VDAC2))
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抗原表位
- C-Term
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适用
- 人, 大鼠, 小鼠, 犬, Cow, Pig
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This VDAC2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 序列
- C-GHKVGLALEL EA
- 特异性
- This antibody detects VDAC-2 at C-term.
- 交叉反应 (详细)
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Species reactivity (expected):Mouse, Canine (Dog), Bovine and Pig.
Species reactivity (tested):Human, Rat. - 纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
- 免疫原
- Peptide from C-Terminus of the protein sequence according to NP_003366.2 Genename: VDAC2
- Top Product
- Discover our top product VDAC2 Primary Antibody
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- 应用备注
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Peptide ELISA: Antibody Limit dilution 1/64000. Western blot: 0.3-1.0 μg/mL. Approx 30 kDa band observed in Human Brain and HumanTestis lysates (calculated MW of 31.0 kDa according to NP_003366.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.
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Relationship of sperm small heat-shock protein 10 and voltage-dependent anion channel 2 with semen freezability in boars." in: Theriogenology, Vol. 82, Issue 3, pp. 418-26, (2014) (PubMed).
: "Expression and activity of alcohol and aldehyde dehydrogenases in melanoma cells and in melanocytes." in: Journal of cellular biochemistry, Vol. 113, Issue 3, pp. 792-9, (2012) (PubMed).
: "Reduction in paracrine Wnt3 factors during aging causes impaired adult neurogenesis." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 10, pp. 3570-82, (2011) (PubMed).
: "BAG1 modulates huntingtin toxicity, aggregation, degradation, and subcellular distribution." in: Journal of neurochemistry, Vol. 111, Issue 3, pp. 801-7, (2009) (PubMed).
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Relationship of sperm small heat-shock protein 10 and voltage-dependent anion channel 2 with semen freezability in boars." in: Theriogenology, Vol. 82, Issue 3, pp. 418-26, (2014) (PubMed).
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- 抗原
- VDAC2 (Voltage-Dependent Anion Channel 2 (VDAC2))
- 别名
- VDAC2 (VDAC2 产品)
- 别名
- POR antibody, Vdac6 antibody, mVDAC2 antibody, mVDAC6 antibody, wu:fa01a08 antibody, wu:fa98a10 antibody, wu:fb50g11 antibody, zgc:55795 antibody, zgc:77621 antibody, vdac2 antibody, VDAC2 antibody, ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 2 antibody, ATVDAC2 antibody, K9I9.6 antibody, K9I9_6 antibody, voltage dependent anion channel 2 antibody, voltage dependent anion channel 2 antibody, voltage-dependent anion channel 2 antibody, voltage-dependent anion channel 2 S homeolog antibody, VDAC2 antibody, Vdac2 antibody, vdac2 antibody, vdac2.S antibody
- 背景
- VDAC2 forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. VDAC2 interacts with hexokinases. It is present in the outer mitochondrial membrane. There are 4 isoforms as result of alternative splicing. It consists mainly of membrane spanning sided beta sheets, and belongs to the eukaryotic mitochondrial porin family.Synonyms: Outer mitochondrial membrane protein porin 2, VDAC-2, Voltage-dependent anion-selective channel protein 2
- 基因ID
- 7417
- NCBI登录号
- NP_003366
- UniProt
- P45880
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