Transgelin 抗体 (C-Term)
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- 抗原 See all Transgelin (TAGLN) 抗体
- Transgelin (TAGLN)
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This Transgelin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 序列
- C-MTGYGRPRQI IS
- 特异性
- This antibody detects Transgelin (TAGLN) at C-term.
- 交叉反应 (详细)
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Species reactivity (expected):Mouse, Rat, Canine (Dog), Cow.
Species reactivity (tested):Human. - 纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
- 免疫原
- Peptide with sequence from the C-Terminus of the protein sequence according to NP_003177.2. Genename: TAGLN
- Top Product
- Discover our top product TAGLN Primary Antibody
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- 应用备注
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Peptide ELISA: Limit Dilution: 1/32000. Western blot: 0.01-0.03 mg/mL. Approx 24 kDa band observed in Human Placenta Lysates(calculated MW of 22.4 kDa according to NP_003177.2 and NP_001001522.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin." in: Development (Cambridge, England), Vol. 142, Issue 1, pp. 174-84, (2014) (PubMed).
: "Impaired retrograde membrane traffic through endosomes in a mutant CHO cell defective in phosphatidylserine synthesis." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 17, Issue 8, pp. 728-36, (2012) (PubMed).
: "Myrip couples the capture of secretory granules by the actin-rich cell cortex and their attachment to the plasma membrane." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 7, pp. 2564-77, (2012) (PubMed).
: "Reduction in antioxidant enzyme expression and sustained inflammation enhance tissue damage in the subacute phase of spinal cord contusive injury." in: Journal of biomedical science, Vol. 18, pp. 13, (2011) (PubMed).
: "Molecular evidence of a (pro)renin/ (pro)renin receptor system in human intrauterine tissues in pregnancy and its association with PGHS-2." in: Journal of the renin-angiotensin-aldosterone system : JRAAS, Vol. 12, Issue 3, pp. 304-10, (2011) (PubMed).
: "Transforming growth factor-beta1 induces transdifferentiation of myoblasts into myofibroblasts via up-regulation of sphingosine kinase-1/S1P3 axis." in: Molecular biology of the cell, Vol. 21, Issue 6, pp. 1111-24, (2010) (PubMed).
: "KAP1 is associated with peritoneal carcinomatosis in gastric cancer." in: Annals of surgical oncology, Vol. 17, Issue 3, pp. 821-8, (2010) (PubMed).
: "Sphingosine 1-phosphate induces differentiation of adipose tissue-derived mesenchymal stem cells towards smooth muscle cells." in: Cellular and molecular life sciences : CMLS, Vol. 66, Issue 10, pp. 1741-54, (2009) (PubMed).
: "Proteomic profiling of chronic low-frequency stimulated fast muscle." in: Proteomics, Vol. 7, Issue 18, pp. 3417-30, (2007) (PubMed).
: "Nucleocytoplasmic shuttling of the zinc finger protein EZI Is mediated by importin-7-dependent nuclear import and CRM1-independent export mechanisms." in: The Journal of biological chemistry, Vol. 282, Issue 44, pp. 32327-37, (2007) (PubMed).
: "Nuclear pregnane X receptor cross-talk with FoxA2 to mediate drug-induced regulation of lipid metabolism in fasting mouse liver." in: The Journal of biological chemistry, Vol. 282, Issue 13, pp. 9768-76, (2007) (PubMed).
: "FGF19 is a target for FOXC1 regulation in ciliary body-derived cells." in: Human molecular genetics, Vol. 15, Issue 21, pp. 3229-40, (2006) (PubMed).
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The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin." in: Development (Cambridge, England), Vol. 142, Issue 1, pp. 174-84, (2014) (PubMed).
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- 抗原
- Transgelin (TAGLN)
- Abstract
- TAGLN 产品
- 别名
- MGC68550 antibody, sm22 antibody, smcc antibody, tagln1 antibody, ws3-10 antibody, MGC107855 antibody, SM22 antibody, SMCC antibody, TAGLN1 antibody, WS3-10 antibody, Sm22 antibody, Sm22a antibody, Ws310 antibody, SM22A antibody, zgc:153186 antibody, transgelin L homeolog antibody, transgelin antibody, tagln.L antibody, tagln antibody, LOC732906 antibody, TAGLN antibody, tagl antibody, LOC100009332 antibody, Tagln antibody
- 背景
- TAGLN is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear.Synonyms: 22 kDa actin-binding protein, SM22, Smooth muscle protein 22-alpha, WS3-10
- 基因ID
- 6876
- NCBI登录号
- NP_003177
- UniProt
- Q01995
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