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GOPC 抗体 (C-Term)

GOPC 适用: 人, Cow, 犬 WB, IF 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374395
发货至: 中国
  • 抗原 See all GOPC 抗体
    GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))
    抗原表位
    • 15
    • 7
    • 7
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 77
    • 33
    • 10
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    人, Cow, 犬
    宿主
    • 76
    • 1
    山羊
    克隆类型
    • 68
    • 9
    多克隆
    标记
    • 29
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GOPC antibody is un-conjugated
    应用范围
    • 39
    • 25
    • 25
    • 14
    • 14
    • 11
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    C-LDDLHTLYHK KSY
    特异性
    This antibody detects PIST / FIG / GOPC at C-term. It is expected to recognize both reported isoforms.
    交叉反应 (详细)
    Species reactivity (expected):Canine (Dog), Cow.
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Peptide from C-Terminus of the protein sequence according to NP_065132.1, NP_001017408.1 Genename: GOPC
    Top Product
    Discover our top product GOPC Primary Antibody
  • 应用备注
    Peptide ELISA: Limit dilution 1: 128000. Western blot: 0.05-0.2 μg/mL. Approx.55 kDa band observed in Human Brain (FrontalCortex) lysates (calculated MW of 50.5 kDa according to NP_065132.1).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))
    别名
    GOPC / PIST (GOPC 产品)
    别名
    DKFZp459H2130 antibody, 2210402P09Rik antibody, AI844555 antibody, CAL antibody, FIG antibody, GOPC1 antibody, PIST antibody, fe38f01 antibody, wu:fe38f01 antibody, zgc:56254 antibody, zgc:65853 antibody, dJ94G16.2 antibody, cal antibody, gopc1 antibody, pist antibody, golgi associated PDZ and coiled-coil motif containing antibody, golgi-associated PDZ and coiled-coil motif containing antibody, golgi-associated PDZ and coiled-coil motif containing S homeolog antibody, GOPC antibody, Gopc antibody, gopc antibody, gopc.S antibody
    背景
    PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner. PIST, a PDZ domain-containing Golgi protein, was discovered in a yeast two-hybrid system as a binding partner to Beclin-1, a Bcl-2-interacting protein homologous to the yeast autophagy gene apg6. Experiments with mutant PIST proteins lacking the PDZ domain showed that PIST interaction with Beclin-1 through its coiled-coil domain can modulate Beclin-1 activity and suggest that PIST interactions with other proteins through its PDZ domain may regulate the activity of PIST and Beclin-1.Synonyms: CAL, CFTR-associated ligand, FIG, Fused in glioblastoma, Golgi-associated PDZ and coiled-coil motif-containing protein, PDZ protein interacting specifically with TC10
    基因ID
    57120
    NCBI登录号
    NP_065132
    UniProt
    Q9HD26
    途径
    Maintenance of Protein Location, Asymmetric Protein Localization
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