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KDM2B 抗体 (C-Term)

KDM2B 适用: 人, 小鼠, 犬, 大鼠 WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374346
发货至: 中国
  • 抗原 See all KDM2B 抗体
    KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))
    抗原表位
    • 8
    • 7
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    C-Term
    适用
    • 44
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 犬, 大鼠
    宿主
    • 36
    • 12
    • 1
    山羊
    克隆类型
    • 38
    • 11
    多克隆
    标记
    • 16
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This KDM2B antibody is un-conjugated
    应用范围
    • 29
    • 24
    • 16
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    C-FGQVEEKLLQ KLS
    特异性
    This antibody detects FBXL10 / PCCX2 at C-term. It is expected to recognize isoform a (NP_115979.3) only.
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat, DogSpecies reactivity (tested):Human
    纯化方法
    Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
    免疫原
    Peptide from C Terminus of the protein sequence according to NP_115979.3 Genename: KDM2B
    Top Product
    Discover our top product KDM2B Primary Antibody
  • 应用备注
    Peptide ELISA: Limit dilution 1: 32000. Western blot: 1-3 μg/mL. Customer's experiments gave bands at approx 170+90 kDa inlysates of cell line HeLa (calculated MW of 150 kDa according to NP_115979.3).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
  • 抗原
    KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))
    别名
    KDM2B / FBXL10 (KDM2B 产品)
    别名
    CXXC2 antibody, FBXL10 antibody, Fbl10 antibody, JHDM1B antibody, PCCX2 antibody, fbxl10 antibody, wu:fd13a09 antibody, zgc:85787 antibody, KDM2B antibody, Fbxl10 antibody, Cxxc2 antibody, E430001G17 antibody, Jhdm1b antibody, mKIAA3014 antibody, jhdm1b antibody, F6P23.18 antibody, F6P23_18 antibody, lysine demethylase 2B antibody, lysine (K)-specific demethylase 2Ba antibody, microRNA 7107 antibody, lysine (K)-specific demethylase 2B antibody, lysine (K)-specific demethylase 2B L homeolog antibody, F-box/RNI-like superfamily protein antibody, KDM2B antibody, kdm2ba antibody, Kdm2b antibody, MIR7107 antibody, kdm2b.L antibody, AT2G17020 antibody
    背景
    KDM2B is a histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylted H3 'Lys-36'. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.Synonyms: CXXC-type zinc finger protein 2, CXXC2, F-box and leucine-rich repeat protein 10, F-box protein FBL10, F-box/LRR-repeat protein 10, FBL10, JEMMA, JHDM1B, JmjC domain-containing histone demethylation protein 1B, Jumonji domain-containing EMSY-interactor methyltransferase motif protein, Lysine-specific demethylase 2B, PCCX2, Protein-containing CXXC domain 2, [Histone-H3]-lysine-36 demethylase 1B
    基因ID
    84678
    NCBI登录号
    NP_115979
    UniProt
    Q8NHM5
    途径
    Tube Formation, Warburg Effect
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