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IPO7 抗体 (C-Term)

IPO7 适用: 人, 小鼠, Cow, 大鼠, 犬 WB, IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374249
发货至: 中国
  • 抗原 See all IPO7 抗体
    IPO7 (Importin 7 (IPO7))
    抗原表位
    • 15
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 50
    • 21
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, Cow, 大鼠, 犬
    宿主
    • 48
    • 1
    • 1
    山羊
    克隆类型
    • 49
    • 1
    多克隆
    标记
    • 19
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IPO7 antibody is un-conjugated
    应用范围
    • 42
    • 19
    • 19
    • 13
    • 13
    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    序列
    C-SSFNFGGPAP GMN
    特异性
    This antibody detects RanBP7/Importin-7 at C-term.
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat, Dog, CowSpecies reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Synthetic peptide from C-terminus of Human IPO7 (NP_006382.1). Genename: IPO7
    Top Product
    Discover our top product IPO7 Primary Antibody
  • 应用备注
    Peptide ELISA: Limit dilution: 1/32000. Western blot: 0.1-1 μg/mL. Approx 120 kDa band observed in Human Brain lysates(predicted MW of 110 kDa according to NP_006382.1). Please note that an approx 30 kDaband of unknown identity is also consistently observed. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing of 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    IPO7 (Importin 7 (IPO7))
    别名
    RanBP7 / Importin-7 (IPO7 产品)
    别名
    fb33d09 antibody, wu:fb33d09 antibody, zgc:66425 antibody, zgc:76878 antibody, imp7 antibody, ranbp7 antibody, Imp7 antibody, RANBP7 antibody, A330055O14Rik antibody, C330016G14 antibody, Ranbp7 antibody, importin 7 antibody, importin 7 S homeolog antibody, importin-7 antibody, karyopherin antibody, ipo7 antibody, ipo7.S antibody, IPO7 antibody, CpipJ_CPIJ002096 antibody, PTRG_08544 antibody, SJAG_03693 antibody, NAEGRDRAFT_71372 antibody, VDBG_01971 antibody, MGYG_08162 antibody, Tsp_01943 antibody, Tsp_01946 antibody, Ipo7 antibody
    背景
    The Importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran binding site of importin beta. Similar to importin beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta like transport receptors, namely importin beta itself, transportin, RanBP5 and Importin 7, directly bind and import ribosomal proteins.Synonyms: IMP7, IPO7, Ran-binding protein 7
    基因ID
    10527
    NCBI登录号
    NP_006382
    UniProt
    O95373
    途径
    Protein targeting to Nucleus
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