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ERK1 抗体 (pThr202, Tyr204)

Name: ERK1 抗体 (pThr202, Tyr204)
SKU: ABIN372623
Availability: OutOfStock

MAPK3 适用: 人, 小鼠, 大鼠, 小鸡, 犬, Cow, 斑马鱼, 非洲爪蟾, Non-Human Primate WB, IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated

Image no. 1 for anti-Mitogen-Activated Protein Kinase 3 (MAPK3) (pThr202), (Tyr204) antibody (ABIN372623) (ERK1 抗体 (pThr202, Tyr204))

1 image

(1 reference)

产品编号 ABIN372623

发货至: 中国

Datasheet as PDF

抗原 See all ERK1 (MAPK3) 抗体

ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))
抗原表位
64

43

20

16

15

15

10

10

9

9

8

7

6

6

5

4

3

3

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

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pThr202, Tyr204
适用
212

157

131

42

20

19

15

10

9

9

9

7

6

5

5

4

3

2

1

1

1

1
人, 小鼠, 大鼠, 小鸡, 犬, Cow, 斑马鱼, 非洲爪蟾, Non-Human Primate
宿主
219

28

3

1

1
兔
Compatible Secondaries
克隆类型
202

50
多克隆
标记
105

17

16

14

7

7

5

5

5

5

5

5

5

5

5

5

5

3

3

3

3

3

3

2

2

2

2

2

2

1
This ERK1 antibody is un-conjugated
应用范围
200

78

67

65

65

42

38

34

30

21

17

11

7

5

3

2

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

特异性

Recognizes the ~42k-44k ERK/MAPK phosphorylated at Thr202 and Tyr204. Immunolabeling is blocked by the phosphopeptide used as antigen but not by the corresponding dephosphopeptide. The immunolabeling is completely eliminated by lambda-phosphatase.

交叉反应（详细）

Species reactivity (expected):Bovine, Canine, Chicken, Mouse, non-Human Primates, Xenopus and ZebrafishSpecies reactivity (tested):Human and Rat.

纯化方法

Sequential Chromatography on phospho- and dephosphopeptide affinity columns.

免疫原

Phosphopeptide corresponding to amino acid residues surrounding the phospho-Thr202 and Tyr204 of rat ERK/MAPK.

亚型

IgG

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anti-Mitogen-Activated Protein Kinase 3 (MAPK3) antibody
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anti-Mitogen-Activated Protein Kinase 3 (MAPK3) (AA 1-100) antibody
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anti-Mitogen-Activated Protein Kinase 3 (MAPK3) (pTyr204) antibody
MAPK3 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

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MAPK3 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 1E5 unconjugated

anti-Mitogen-Activated Protein Kinase 3 (MAPK3) (AA 75-312) antibody
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anti-Mitogen-Activated Protein Kinase 3 (MAPK3) (AA 75-312) antibody
MAPK3 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated

anti-Mitogen-Activated Protein Kinase 3 (MAPK3) (pThr185), (pThr202), (pTyr187), (pTyr204) antibody
MAPK3 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 3 (MAPK3) (AA 279-379) antibody
MAPK3 适用: 人 WB, ELISA, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 3C9 unconjugated

anti-Mitogen-Activated Protein Kinase 3 (MAPK3) (pThr202), (pTyr204) antibody
MAPK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western Blot: 1/1000. Immunohistochemistry: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
状态

Liquid

缓冲液

10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

注意事项

Avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store the antibody undiluted (in aliquots) at-20 °C.
Chaudhuri, Ghate, Singh, Mandal: "Methyl gallate isolated from Spondias pinnata exhibits anticancer activity against human glioblastoma by induction of apoptosis and sustained extracellular signal-regulated kinase 1/2 activation." in: Pharmacognosy magazine, Vol. 11, Issue 42, pp. 269-76, (2015) (PubMed).
抗原

ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

别名

MAPK3 / ERK1 (MAPK3 产品)

背景

Extracellular-Signal Regulated Kinase/Mitogen-Activated Protein Kinase (ERK/MAPK) is an integral component of cellular signaling during mitogenesis and differentiation of mitotic cells and also is thought to play a key role in learning and memory (Adams and Sweatt, 2002, Ahn, 1993, Tanoue and Nishida, 2003, Johnson and Lapadat, 2002). The activity of this kinase is regulated by dual phosphorylation at Thr202 and Tyr204 (Ahn, 1993).Synonyms: ERK-1, ERT2, Extracellular signal-regulated kinase 1, Insulin-stimulated MAP2 kinase, MAP kinase 3, MAP kinase isoform p44, MAPK 3, Microtubule-associated protein 2 kinase, Mitogen-activated protein kinase 1, Mitogen-activated protein kinase 3, PRKM3, p44-ERK1, p44-MAPK

基因ID

5595

NCBI登录号

NP_002737

UniProt

P27361

途径

MAPK Pathway, RTK signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, S100 Proteins