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MARCH4 抗体 (AA 300-350)

MARCH4 适用: 人, 小鼠, 大鼠, 犬, 小鸡, 马, Opossum, 斑马鱼, Chimpanzee WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN372267
发货至: 中国
  • 抗原 See all MARCH4 抗体
    MARCH4 (Membrane-Associated Ring Finger (C3HC4) 4, E3 Ubiquitin Protein Ligase (MARCH4))
    抗原表位
    • 9
    • 8
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 300-350
    适用
    • 43
    • 26
    • 22
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 小鸡, 马, Opossum, 斑马鱼, Chimpanzee
    宿主
    • 41
    • 1
    • 1
    克隆类型
    • 43
    多克隆
    标记
    • 14
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MARCH4 antibody is un-conjugated
    应用范围
    • 37
    • 19
    • 13
    • 4
    • 3
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody recognizes Membrane-Associated Ring Finger 4 (MARCH4).
    交叉反应 (详细)
    Species reactivity (expected):Chimpanzee, Chicken, Dog (Canine), Horse, Mouse, Opossum, Rat and ZebrafishSpecies reactivity (tested):Human.
    纯化方法
    Immunoaffinity Chromatography.
    免疫原
    Synthetic peptide corresponding to a portion of the amino acids 300-350 of human RNF174.
    亚型
    IgG
    Top Product
    Discover our top product MARCH4 Primary Antibody
  • 应用备注
    Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western Blot: 0.5-2.0 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % Sodium Azide as preservative and 0.05 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    MARCH4 (Membrane-Associated Ring Finger (C3HC4) 4, E3 Ubiquitin Protein Ligase (MARCH4))
    别名
    MARCH4 / RNF174 (MARCH4 产品)
    别名
    MARCH-IV antibody, RNF174 antibody, BC056494 antibody, mKIAA1399 antibody, MARCH4 antibody, si:ch211-239d11.2 antibody, membrane associated ring-CH-type finger 4 antibody, membrane-associated ring finger (C3HC4) 4 antibody, MARCH4 antibody, March4 antibody, march4 antibody
    背景
    MARCH4, an E3 ubiquitin protein ligase, may mediate ubiquitination of MHC I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin protein ligases accept ubiquitin from an E2 ubiquitin conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.Synonyms: E3 ubiquitin-protein ligase MARCH4, KIAA1399, MARCH-IV, Membrane-associated RING finger protein 4, Membrane-associated RING-CH protein IV, RING finger protein 174
    分子量
    46 kDa
    基因ID
    57574
    NCBI登录号
    NP_065865
    UniProt
    Q9P2E8
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