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PTGDS 抗体

PTGDS 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN363611
发货至: 中国
  • 抗原 See all PTGDS 抗体
    PTGDS (Prostaglandin D2 Synthase (PTGDS))
    适用
    • 31
    • 11
    • 6
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    • 4
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    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 27
    • 5
    • 2
    • 1
    • 1
    克隆类型
    • 33
    • 3
    多克隆
    标记
    • 26
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PTGDS antibody is un-conjugated
    应用范围
    • 25
    • 14
    • 13
    • 4
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    • 2
    • 1
    Western Blotting (WB)
    特异性
    Reacts with Prostaglandin D Synthase from human, mouse, rat, bovine, canine, feline, primate and rabbit
    纯化方法
    Antigen affinity purified
    免疫原
    The epitope recognized by this antibody maps to region within residue 120-190 of human PTGDS
    Top Product
    Discover our top product PTGDS Primary Antibody
  • 应用备注

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only:
    - WB : 2 μg/mL

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS, glycerol 30 % , Sodium azide 0.1 %
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
    有效期
    6 months
  • 抗原
    PTGDS (Prostaglandin D2 Synthase (PTGDS))
    别名
    Prostaglandin D Synthase (PTGDS) (PTGDS 产品)
    别名
    6PGD antibody, GSTS antibody, GSTS1-1 antibody, PGD2 antibody, PGDS antibody, L-PGDS antibody, LPGDS antibody, PDS antibody, PGDS2 antibody, H-PGDS antibody, Ptgds2 antibody, 21kDa antibody, Ptgs3 antibody, PH2DISO antibody, phosphogluconate dehydrogenase antibody, hematopoietic prostaglandin D synthase antibody, prostaglandin D2 synthase antibody, prostaglandin D2 synthase (brain) antibody, prostaglandin D synthase antibody, prostaglandin D2 synthase 21kDa (brain) antibody, PGD antibody, HPGDS antibody, PTGDS antibody, Hpgds antibody, Ptgds antibody, LOC100009453 antibody
    背景
    The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. PTGDS has also been implicated in the development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement (NREM) sleep. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system. PTGDS is the most abundant protein in the cerebral spinal fluidand recent evidence suggests that PTGDS acts as a Beta-Amyloid chaperone and may have a role in the deposition of Ab plaques in Alzheimer's disease.
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