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IGF1R 抗体 (AA 1163-1167)

This anti-IGF1R antibody is a 兔 多克隆 antibody detecting IGF1R in WB. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN362638
发货至: 中国

Quick Overview for IGF1R 抗体 (AA 1163-1167) (ABIN362638)

抗原

See all IGF1R 抗体
IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This IGF1R antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1163-1167

    特异性

    The antibody detects endogenous level of total IGF-1R protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Peptide sequence around AA 1163-1167, 1164-1168 (T-D-Y-Y-R-K) derived from Human IGF-1R . Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

    亚型

    IgG
  • 应用备注

    Western blotting: 1:500-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Haghir, Rezaee, Nomani, Sankian, Kheradmand, Hami: "Sexual dimorphism in expression of insulin and insulin-like growth factor-I receptors in developing rat cerebellum." in: Cellular and molecular neurobiology, Vol. 33, Issue 3, pp. 369-77, (2013) (PubMed).

    Han, Quirion, Zheng: "WITHDRAWN: Glutamate Attenuates IGF-1 Receptor Signaling via NR2B containing NMDA Receptors 3 and neuronal Nitric Oxide Synthase." in: Biochemical and biophysical research communications, (2011) (PubMed).

  • 抗原

    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

    别名

    IGF-1R

    背景

    This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.

    分子量

    95 kDa

    NCBI登录号

    NP_000866

    UniProt

    P08069

    途径

    RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
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