SNCA 抗体 (pTyr125)
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- 抗原 See all SNCA 抗体
- SNCA (Synuclein, alpha (SNCA))
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抗原表位
- pTyr125
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SNCA antibody is un-conjugated
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应用范围
- Immunofluorescence (IF)
- 特异性
- The antibody detects endogenous level of a-Synuclein only when phosphorylated at tyrosine 125.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed bychromatography using non-phosphopeptide corresponding to the phosphorylation site.
- 免疫原
- Peptide sequence around phosphorylation site of pTyr125 (E-A-Y (p) -E-M) derived from Human a-Synuclein. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- 亚型
- IgG
- Top Product
- Discover our top product SNCA Primary Antibody
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anti-Synuclein, alpha (SNCA) (pSer129) antibody
SNCA 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (Atto 488)SNCA 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 488
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (Atto 390)SNCA 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 390
anti-Synuclein, alpha (SNCA) (AA 124-134), (pSer129) antibodySNCA 适用: 人 WB, ELISA, IHC, ICC 宿主: 兔 Monoclonal J18 unconjugated
anti-Synuclein, alpha (SNCA) (AA 124-134), (pSer129) antibody (HRP)SNCA 适用: 人 WB, ELISA, IHC, ICC 宿主: 兔 Monoclonal J18 HRP
anti-Synuclein, alpha (SNCA) (AA 124-134), (pSer129) antibody (FITC)SNCA 适用: 人 WB, ELISA, IHC, ICC 宿主: 兔 Monoclonal J18 FITC
anti-Synuclein, alpha (SNCA) (AA 124-134), (pSer129) antibody (PE)SNCA 适用: 人 WB, ELISA, IHC, ICC 宿主: 兔 Monoclonal J18 PE
anti-Synuclein, alpha (SNCA) (AA 61-140) antibodySNCA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibodySNCA 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (HRP)SNCA 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal HRP
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- 应用备注
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Western blotting: 1:500-1:1000
Immunofluorescence: 1:100-1:200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- 抗原
- SNCA (Synuclein, alpha (SNCA))
- 别名
- alpha-Synuclein (SNCA 产品)
- 别名
- snca antibody, MGC64356 antibody, LOC619283 antibody, NACP antibody, alphaSYN antibody, PARK1 antibody, PARK4 antibody, PD1 antibody, synuclein alpha L homeolog antibody, alpha-synuclein antibody, synuclein alpha antibody, synuclein, alpha antibody, snca.L antibody, LOC619283 antibody, SNCA antibody, Snca antibody
- 背景
- SncA is a member of the synuclein family of structurally related proteins that are prominently expressed in the central nervous system, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and SncA and Snc-Beta inhibit phospholipase D2 selectively. SncA may serve to integrate presynaptic signaling and membrane trafficking. Aggregated SncA proteins form brain lesions that are hallmarks of neurodegenerative synucleinopathies. Defects in SncA play a role in the pathogenesis of Parkinson disease. SncA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer disease. SncA shares 95% sequence homology with rat SncA. Rat SncA is specifically expressed in brain and is associated with synaptosomal membranes in neurons
- 分子量
- 18 kDa
- NCBI登录号
- NP_000336
- UniProt
- P37840
- 途径
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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