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ATF2 抗体 (pSer44, pSer62)

ATF2 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN361930
发货至: 中国
  • 抗原 See all ATF2 抗体
    ATF2 (Activating Transcription Factor 2 (ATF2))
    抗原表位
    • 49
    • 36
    • 26
    • 26
    • 24
    • 24
    • 23
    • 23
    • 15
    • 15
    • 14
    • 14
    • 12
    • 10
    • 9
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer44, pSer62
    适用
    • 295
    • 229
    • 206
    • 16
    • 12
    • 11
    • 8
    • 7
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 327
    • 12
    • 2
    • 1
    克隆类型
    • 313
    • 29
    多克隆
    标记
    • 154
    • 20
    • 16
    • 16
    • 16
    • 15
    • 15
    • 15
    • 13
    • 12
    • 9
    • 8
    • 8
    • 8
    • 8
    • 5
    • 4
    This ATF2 antibody is un-conjugated
    应用范围
    • 241
    • 118
    • 112
    • 111
    • 76
    • 61
    • 59
    • 35
    • 33
    • 22
    • 15
    • 10
    • 6
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC)
    特异性
    The antibody detects endogenous level of ATF-2 only when phosphorylated at serine 62 or 44.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    免疫原
    Peptide sequence around phosphorylation site of pSer62 or 44 (N-D-S (p) -V-I) derived from Human ATF2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
    亚型
    IgG
    Top Product
    Discover our top product ATF2 Primary Antibody
  • 应用备注
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原
    ATF2 (Activating Transcription Factor 2 (ATF2))
    别名
    ATF2 (ATF2 产品)
    别名
    CRE-BP1 antibody, CREB2 antibody, HB16 antibody, TREB7 antibody, CG12850 antibody, CG3749 antibody, dATF-2 antibody, DmelCG30420 antibody, CG30420 antibody, CHN1 antibody, Atf-2 antibody, CRE-BP antibody, Creb2 antibody, D130078H02Rik antibody, D18875 antibody, Tg(Gzma-Klra1)7Wum antibody, mXBP antibody, atf2-A antibody, atf2l antibody, activating transcription factor 2 antibody, Activating transcription factor-2 antibody, activating transcription factor 2 S homeolog antibody, ATF2 antibody, Atf-2 antibody, Atf2 antibody, atf2.S antibody, atf2 antibody
    背景
    Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.
    分子量
    65-75 kDa
    NCBI登录号
    NP_001871
    UniProt
    P15336
    途径
    MAPK Pathway, RTK signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
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