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ATF2 抗体 (pSer490, pSer498)

This 兔 多克隆 antibody specifically detects ATF2 in WB, IHC, ELISA 和 ICC. It exhibits reactivity toward 人. It has been mentioned in 3+ publications
产品编号 ABIN361474
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ATF2 抗体 (pSer490, pSer498) (ABIN361474)

抗原

See all ATF2 抗体
ATF2 (Activating Transcription Factor 2 (ATF2))

适用

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宿主

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克隆类型

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多克隆

标记

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This ATF2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
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    pSer490, pSer498

    特异性

    Specific for endogenous levels of the ~74 kDa ATF2 protein phosphorylated at Ser490,498. The antibody also recognizes the phosphorylated ~54 kDa splice form of ATF2.

    交叉反应

    人, 小鼠

    预测反应

    rat

    产品特性

    Our ATF2 (Ser490,498) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects ATF2 (Ser490,498) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC, ICC.

    纯化方法

    Prepared from rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

    免疫原

    Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser490/498 of human ATF2, conjugated to keyhole limpet hemocyanin (KLH).

    亚型

    IgG
  • 应用备注

    Dilution Range: ICC: 1:500

    Dilution Range: WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

    储存条件

    -20 °C

    储存方法

    Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

    有效期

    12 months
  • Muñoz, Kawahara, Yannone: "An autonomous chromatin/DNA-PK mechanism for localized DNA damage signaling in mammalian cells." in: Nucleic acids research, Vol. 41, Issue 5, pp. 2894-906, (2013) (PubMed).

    Wang, Saha, Hada, Anderson, Pluth, ONeill, Cucinotta: "Novel Smad proteins localize to IR-induced double-strand breaks: interplay between TGFβ and ATM pathways." in: Nucleic acids research, Vol. 41, Issue 2, pp. 933-42, (2013) (PubMed).

    Chappell, Whalen, Gurai, Ponomarev, Cucinotta, Pluth: "Analysis of Flow Cytometry DNA Damage Response Protein Activation Kinetics after Exposure to X Rays and High-Energy Iron Nuclei." in: Radiation research, (2010) (PubMed).

  • 抗原

    ATF2 (Activating Transcription Factor 2 (ATF2))

    别名

    ATF2

    背景

    Synonyms: Activating transcription factor 2 antibody, Activating transcription factor 2 splice variant ATF2 var2 antibody, ATF 2 antibody, Atf-2 antibody, Atf2 antibody, ATF2 protein antibody, ATF2_HUMAN antibody, cAMP Response Element Binding Protein 2 antibody, cAMP response element binding protein CRE BP1 antibody, cAMP response element-binding protein CRE-BP1 antibody, cAMP responsive element binding protein 2, formerly antibody, cAMP-dependent transcription factor ATF-2 antibody, cAMP-responsive element-binding protein 2 antibody, CRE BP1 antibody, CRE-BP antibody, CREB 2 antibody, CREB-2 antibody, CREB2 antibody, CREBP1 antibody, Cyclic AMP dependent transcription factor ATF 2 antibody, Cyclic AMP-dependent transcription factor ATF-2 antibody, Cyclic AMP-responsive element-binding protein 2 antibody, D130078H02Rik antibody, D18875 antibody, HB 16 antibody, HB16 antibody, Histone acetyltransferase ATF2 antibody, MGC105211 antibody, MGC105222 antibody, MGC111558 antibody, MGC142504 antibody, mXBP antibody, MXBP protein antibody, Tg(Gzma-Klra1)7Wum antibody, TREB 7 antibody, TREB7 antibody

    Description Logic: Our ATF2 (Ser490,498) rabbit polyclonal phosphospecific primary antibody is produced . It detects ATF2 (Ser490,498) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC, ICC.

    Gene Name Alternatives: ATF2

    分子量

    74 kDa

    基因ID

    1386

    UniProt

    P15336

    途径

    MAPK Pathway, RTK signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
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