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- 抗原 See all Kv2.2 (KCNB2) 抗体
- Kv2.2 (KCNB2) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 2 (KCNB2))
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Kv2.2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- Specific for the ~125k voltage gated potassium channel, Kv 2.2 subunit.
- 交叉反应
- 大鼠
- 纯化方法
- Antigen Affinity Purified from Pooled Serum
- 免疫原
- Synthetic peptide corresponding to amino acid residues specific to the Kv2.2 subunit conjugated to KLH
- Top Product
- Discover our top product KCNB2 Primary Antibody
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- 应用备注
- Recommended Dilution: WB: 1:1000 IHC (frozen sections, unpublished observations): 1:1000 Quality Control: Western blots performed on each lot.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
- 储存条件
- -20 °C
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Localization of Kv2.2 protein in Xenopus laevis embryos and tadpoles." in: The Journal of comparative neurology, Vol. 510, Issue 5, pp. 508-24, (2008) (PubMed).
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Localization of Kv2.2 protein in Xenopus laevis embryos and tadpoles." in: The Journal of comparative neurology, Vol. 510, Issue 5, pp. 508-24, (2008) (PubMed).
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- 抗原
- Kv2.2 (KCNB2) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 2 (KCNB2))
- 别名
- KCNB2 (KCNB2 产品)
- 别名
- KCNB2 antibody, si:ch211-193n21.1 antibody, Kv2.2 antibody, 9630047L19Rik antibody, BB130875 antibody, XShab12 antibody, kcnb2 antibody, KV2.2 antibody, potassium voltage-gated channel subfamily B member 2 antibody, potassium voltage-gated channel, Shab-related subfamily, member 2 antibody, potassium channel, voltage gated Shab related subfamily B, member 2 antibody, potassium voltage gated channel, Shab-related subfamily, member 2 antibody, potassium channel, voltage gated Shab related subfamily B, member 2 S homeolog antibody, KCNB2 antibody, kcnb2 antibody, LOC100051372 antibody, Kcnb2 antibody, kcnb2.S antibody
- 背景
- Voltage-gated K+ channels are important determinants of neuronal membrane excitability (Pongs, 1999). Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. The delayed rectifier-type (IK)channels (Kv1.5, Kv2.1, and Kv2.2) are expressed on all neuronal somata and proximal dendrites and are also found in a wide variety of non-neuronal cells types including pancreatic islets, alveolar cells and cardiac myocytes (Hwang et al., 1993, Yan et al., 2004, Michaelevski et al., 2003). Kv2.1 and Kv2.2 form distinct populations of K+ channels and these subunits are thought to be primarily responsible for IK in superior cervical ganglion cells (Blaine and Ribera, 1998, Burger and Ribera, 1996). Anti-Voltage Gated Potassium Channel, Kv2.2-Subunit Western blot of rat brain homogenate showing specific immunolabeling of the ~125k voltage-gated potassium channel, Kv2.2 (Control). The immunolabeling is blocked by preadsorption with the peptide used as antigen (Peptide Block).
- 分子量
- '100 kDa
- 基因ID
- 621349
- UniProt
- Q63099
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