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Kv2.2 抗体

KCNB2 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN361380
发货至: 中国
  • 抗原 See all Kv2.2 (KCNB2) 抗体
    Kv2.2 (KCNB2) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 2 (KCNB2))
    适用
    • 21
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    大鼠
    宿主
    • 33
    • 3
    克隆类型
    • 34
    • 2
    多克隆
    标记
    • 12
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    • 2
    • 1
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    This Kv2.2 antibody is un-conjugated
    应用范围
    • 36
    • 16
    • 13
    • 13
    • 4
    • 4
    • 3
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    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    Specific for the ~125k voltage gated potassium channel, Kv 2.2 subunit.
    交叉反应
    大鼠
    纯化方法
    Antigen Affinity Purified from Pooled Serum
    免疫原
    Synthetic peptide corresponding to amino acid residues specific to the Kv2.2 subunit conjugated to KLH
    Top Product
    Discover our top product KCNB2 Primary Antibody
  • 应用备注
    Recommended Dilution: WB: 1:1000 IHC (frozen sections, unpublished observations): 1:1000 Quality Control: Western blots performed on each lot.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
    储存条件
    -20 °C
  • Gravagna, Knoeckel, Taylor, Hultgren, Ribera: "Localization of Kv2.2 protein in Xenopus laevis embryos and tadpoles." in: The Journal of comparative neurology, Vol. 510, Issue 5, pp. 508-24, (2008) (PubMed).

  • 抗原
    Kv2.2 (KCNB2) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 2 (KCNB2))
    别名
    KCNB2 (KCNB2 产品)
    别名
    KCNB2 antibody, si:ch211-193n21.1 antibody, Kv2.2 antibody, 9630047L19Rik antibody, BB130875 antibody, XShab12 antibody, kcnb2 antibody, KV2.2 antibody, potassium voltage-gated channel subfamily B member 2 antibody, potassium voltage-gated channel, Shab-related subfamily, member 2 antibody, potassium channel, voltage gated Shab related subfamily B, member 2 antibody, potassium voltage gated channel, Shab-related subfamily, member 2 antibody, potassium channel, voltage gated Shab related subfamily B, member 2 S homeolog antibody, KCNB2 antibody, kcnb2 antibody, LOC100051372 antibody, Kcnb2 antibody, kcnb2.S antibody
    背景
    Voltage-gated K+ channels are important determinants of neuronal membrane excitability (Pongs, 1999). Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. The delayed rectifier-type (IK)channels (Kv1.5, Kv2.1, and Kv2.2) are expressed on all neuronal somata and proximal dendrites and are also found in a wide variety of non-neuronal cells types including pancreatic islets, alveolar cells and cardiac myocytes (Hwang et al., 1993, Yan et al., 2004, Michaelevski et al., 2003). Kv2.1 and Kv2.2 form distinct populations of K+ channels and these subunits are thought to be primarily responsible for IK in superior cervical ganglion cells (Blaine and Ribera, 1998, Burger and Ribera, 1996). Anti-Voltage Gated Potassium Channel, Kv2.2-Subunit Western blot of rat brain homogenate showing specific immunolabeling of the ~125k voltage-gated potassium channel, Kv2.2 (Control). The immunolabeling is blocked by preadsorption with the peptide used as antigen (Peptide Block).
    分子量
    '100 kDa
    基因ID
    621349
    UniProt
    Q63099
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