Nuclear Stain of Multiple Gene Products Including Nup62, Nup133 抗体
适用: Saccharomyces cerevisiae
IF
宿主: 小鼠
Monoclonal
39C7
unconjugated
1 image
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- 抗原
- Nuclear Stain of Multiple Gene Products Including Nup62, Nup133
- 适用
- Saccharomyces cerevisiae
- 宿主
- 小鼠
- 克隆类型
- 单克隆
- 应用范围
- Immunofluorescence (IF)
- 特异性
- Reacts with a nuclear pore complex protein.
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Protein G purified culture supernatant
- 免疫原
- Yeast nuclear preparations
- 克隆位点
- 39C7
- 亚型
- IgG1
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- 应用备注
- Recommended Dilution: IF: 1:50-1:100 Quality Control: Immunofluorescence performed on each lot.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- total IgG fraction + 10 mM Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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- 抗原
- Nuclear Stain of Multiple Gene Products Including Nup62, Nup133
- 背景
- The nuclear pore complex (NPC) is a very large structure made up of at least 50 different proteins that span the double membrane of the nuclear envelope functioning as a gateway for macromolecular traffic between the cytoplasm and the nucleus (Nakielny and Dreyfuss,1999). Discrete nuclear pore complex proteins or nucleoporins such as NUP98, NUP180 and p62 have been implicated in autoimmune disease and cancer. Patients with primary biliary cirrhosis (PBC) frequently produce autoantibodies against p62 and NUP180 (Wilken et al., 1993, Nesher et al., 2001) while NUP98 translocations have been found in patients with acute myelogenous leukemia (AML) (Jaju et al. 2001).
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