NBL1 抗体
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- 抗原 See all NBL1 抗体
- NBL1 (Neuroblastoma 1, DAN Family BMP Antagonist (NBL1))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This NBL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody detects Mouse DAN in Western blotting.
- 纯化方法
- Protein A/G affinity chromatography
- 免疫原
- Recombinant DAN
- 克隆位点
- 7K12
- 亚型
- IgG2
- Top Product
- Discover our top product NBL1 Primary Antibody
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anti-Neuroblastoma 1, DAN Family BMP Antagonist (NBL1) (AA 1-180) antibody
NBL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Neuroblastoma 1, DAN Family BMP Antagonist (NBL1) (C-Term) antibodyNBL1 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neuroblastoma 1, DAN Family BMP Antagonist (NBL1) (AA 21-130) antibodyNBL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G5 unconjugated
anti-Neuroblastoma 1, DAN Family BMP Antagonist (NBL1) (AA 131-180) antibodyNBL1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuroblastoma 1, DAN Family BMP Antagonist (NBL1) (C-Term) antibodyNBL1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuroblastoma 1, DAN Family BMP Antagonist (NBL1) (AA 17-181) antibodyNBL1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Neuroblastoma 1, DAN Family BMP Antagonist (NBL1) (AA 21-32) antibodyVerified NBL1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Neuroblastoma 1, DAN Family BMP Antagonist (NBL1) (C-Term) antibodyNBL1 适用: 人, Cow, 犬, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Neuroblastoma 1, DAN Family BMP Antagonist (NBL1) (C-Term) antibodyNBL1 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 溶解方式
- Restore with 0.2 mL sterile PBS and the final concentration is 0.5 mg/mL.
- 缓冲液
- 0.2 μm filtered PBS, None
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- NBL1 (Neuroblastoma 1, DAN Family BMP Antagonist (NBL1))
- 别名
- NBL1 (NBL1 产品)
- 别名
- D1S1733E antibody, DAN antibody, DAND1 antibody, NB antibody, NO3 antibody, D4H1S1733E antibody, Dana antibody, dand1 antibody, nbl1-a antibody, no3 antibody, 4.1N antibody, Epb41l1 antibody, NBL1 antibody, mKIAA0338 antibody, C1orf151-NBL1 antibody, dan antibody, zgc:77251 antibody, neuroblastoma 1, DAN family BMP antagonist antibody, neuroblastoma, suppression of tumorigenicity 1 antibody, neuroblastoma 1, DAN family BMP antagonist L homeolog antibody, neuroblastoma suppressor of tumorigenicity 1 antibody, erythrocyte membrane protein band 4.1 like 1 antibody, MINOS1-NBL1 readthrough antibody, NBL1 antibody, Nbl1 antibody, nbl1.L antibody, LOC535280 antibody, Epb41l1 antibody, MINOS1-NBL1 antibody, nbl1 antibody
- 背景
- DAN (differential screening-selected gene aberrative in neuroblastoma) was initially identified as a gene whose expression is downregulated in srctransformed rat fibroblasts. DAN has now been shown to be a prototypical member of the DAN family of secreted glycoproteins that are putative BMP antagonists. DAN family members share a cysteinerich domain that is structurally related to the cysteineknot motif found in TGFβ superfamily ligands. There are at least five mouse DAN family members, including DAN, Gremlin/DRM, Cer1 (Cerberusrelated), Dante and PRDC (protein-related to DAN and cerberus). Additional DAN family members include Xenopus Cerberus, chick Caronte, and C. elegans CeCan 1. Murine DAN binds BMP2 in immunoprecipitation experiments and acts as a BMP antagonist in Xenopus animal cap explants. The DAN family of proteins are thought to act as antagonists by binding BMP ligands and preventing their interactions with signaling receptor complexes. Recombinant mouse DAN have been shown to bind BMP4 in a functional ELISA. It is likely the various DAN family members and other TGFβ BMP antagonists including Noggin, Chordin, Follistatin, and TSG can selectively antagonize the activities of different subsets of TGFβ superfamily ligands. These antagonists represent one of the many elaborate regulatory mechanisms that have evolved to control the bioactivities of the TGFβ superfamily ligands.Synonyms: DAN, DAND1, Neuroblastoma suppressor of tumorigenicity 1
- 基因ID
- 17965
- NCBI登录号
- NP_032701
- UniProt
- Q61477
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