GBL 抗体 (Middle Region)
Quick Overview for GBL 抗体 (Middle Region) (ABIN360719)
抗原
See all GBL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- This antibody reacts to GBL.
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纯化方法
- Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human GBL.
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亚型
- Ig Fraction
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anti-G protein beta subunit-like (GBL) (AA 1-326) antibody
GBL 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-G protein beta subunit-like (GBL) (AA 1-326) antibodyGBL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-G protein beta subunit-like (GBL) (AA 1-326) antibodyGBL 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-G protein beta subunit-like (GBL) (AA 159-220) antibodyGBL 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-G protein beta subunit-like (GBL) (AA 1-326) antibodyGBL 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-G protein beta subunit-like (GBL) (C-Term) antibodyGBL 适用: 人, 小鼠, 大鼠, Cow, 犬, 山羊, 豚鼠, 马, 兔, Pig, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-G protein beta subunit-like (GBL) (AA 140-170) antibodyGBL 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB11669 unconjugated
anti-G protein beta subunit-like (GBL) antibodyGBL 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-G protein beta subunit-like (GBL) antibodyGBL 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/250 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- GBL (G protein beta subunit-like (GBL))
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别名
- LST8 / GBL
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背景
- G? (G protein beta protein subunit-like) is a member of a signaling pathway that regulates mammalian cell growth in response to the presence of nutrients and growth factors. It binds to the kinase domain of TOR (Target of rapamycin, also known as mTOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors. Rapamycin inhibits TOR resulting in reduced cell growth and reduced rates of cell cycle and cell proliferation. TOR is normally associated with G? and an additional regulatory protein RAPTOR, allowing TOR to control protein biosynthesis. The binding of G? to TOR stimulates TOR's kinase activity towards downstream proteins such as RPS6K (ribosomal protein S6 kinase) and the translation factor 4E-BP1 which leads to increased protein translation and cell growth.Synonyms: G protein beta subunit-like, Gable, Mammalian lethal with SEC13 protein 8, Protein GbetaL, TORC subunit LST8, Target of rapamycin complex subunit LST8, mLST8
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基因ID
- 64223, 9606
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UniProt
- Q9BVC4
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途径
- PI3K-Akt Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Autophagy, CXCR4-mediated Signaling Events, BCR Signaling, Warburg Effect
抗原
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