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RUNX2 抗体 (Ser6533)

This anti-RUNX2 antibody is a 兔 多克隆 antibody detecting RUNX2 in WB 和 EIA. Suitable for 人.
产品编号 ABIN360019
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for RUNX2 抗体 (Ser6533) (ABIN360019)

抗原

See all RUNX2 抗体
RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

适用

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宿主

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克隆类型

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多克隆

标记

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This RUNX2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Ser6533

    特异性

    This antibody reacts to RUNX2.

    纯化方法

    Affinity chromatography on Protein A

    免疫原

    KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S533 of human RUNX2.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

    别名

    RUNX2

    背景

    Runx2 is a member of the RUNX family of transcription factors. It is a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in the Runx2 gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).Synonyms: AML-3, AML3, Acute myeloid leukemia 3 protein, CBFA1, Core-binding factor subunit alpha-1, OSF-2, OSF2, Osteoblast-specific transcription factor 2, PEA2-alpha A, PEBP2-alpha A, PEBP2A, Polyomavirus enhancer-binding protein 2 alpha A subunit, Runt-related transcription factor 2, SL3-3 enhancer factor 1 alpha A subunit, SL3/AKV core-binding factor alpha A subunit

    基因ID

    860, 9606

    UniProt

    Q13950
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