DDR2 抗体
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北京 101111
Quick Overview for DDR2 抗体 (ABIN359957)
抗原
See all DDR2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody reacts to TYRO10.
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纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a his tag recombinant protein of human TYRO10.
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亚型
- Ig Fraction
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anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) antibody
DDR2 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 3B11E4 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) antibodyDDR2 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB17713 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) antibodyDDR2 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 245-350) antibodyDDR2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 578-817) antibodyDDR2 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 447-540) antibodyDDR2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (C-Term) antibodyKO Validated DDR2 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) antibodyKD Validated DDR2 适用: 人 WB 宿主: 兔 Monoclonal 25GB2210 unconjugated Recombinant Antibody
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) antibodyDDR2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 816-843) antibodyDDR2 适用: 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
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别名
- CD167b / DDR2
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背景
- Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane and cytoplasmic regions. There are several subclasses of RTKs and TYRO10 belongs to a novel subclass. The deduced amino acid sequence of TYRO10 has a unique extracellular region encompassing a factor VIII-like domain, not previously described for RTKs.Synonyms: CD167 antigen-like family member B, Discoidin domain-containing receptor 2, Discoidin domain-containing receptor tyrosine kinase 2, NTRKR3, Neurotrophic tyrosine kinase receptor-related 3, Receptor protein-tyrosine kinase TKT, TKT, TYRO10, Tyrosine-protein kinase TYRO10
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基因ID
- 4921, 9606
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UniProt
- Q16832
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途径
- RTK signaling
抗原
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