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IGF1R 抗体 (N-Term)

This anti-IGF1R antibody is a 兔 多克隆 antibody detecting IGF1R in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN359877
发货至: 中国
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Quick Overview for IGF1R 抗体 (N-Term) (ABIN359877)

抗原

See all IGF1R 抗体
IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

适用

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克隆类型

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多克隆

标记

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This IGF1R antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    N-Term

    特异性

    This antibody reacts to IGF1 Receptor (IGF1R).

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human IGF1R.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western Blot: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

    别名

    CD221 / IGF1R

    背景

    The IGF1R receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.Synonyms: IGF-I receptor, IGF1 Receptor, Insulin-like growth factor 1 receptor

    基因ID

    3480, 9606

    UniProt

    P08069

    途径

    RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
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