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FAS 抗体 (pTyr291)

FAS 适用: 人 EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN358278
发货至: 中国
  • 抗原 See all FAS 抗体
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    抗原表位
    • 24
    • 16
    • 16
    • 8
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr291
    适用
    • 213
    • 67
    • 62
    • 19
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    宿主
    • 158
    • 89
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    克隆类型
    • 155
    • 100
    • 1
    多克隆
    标记
    • 123
    • 27
    • 25
    • 12
    • 10
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FAS antibody is un-conjugated
    应用范围
    • 165
    • 117
    • 74
    • 65
    • 36
    • 35
    • 31
    • 26
    • 26
    • 20
    • 19
    • 9
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Enzyme Immunoassay (EIA)
    特异性
    This antibody detects FAS pTyr291.
    纯化方法
    Protein A Affinity Chromatography followed by two-step phosphospecific peptide affinity purification.
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr291 of human FAS.
    亚型
    Ig Fraction
    Top Product
    Discover our top product FAS Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Dot Blot: 1/100-1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    别名
    CD95 / FAS (FAS 产品)
    别名
    ALPS1A antibody, APO-1 antibody, APT1 antibody, CD95 antibody, FAS1 antibody, FASTM antibody, TNFRSF6 antibody, AI196731 antibody, APO1 antibody, TNFR6 antibody, Tnfrsf6 antibody, lpr antibody, Fas cell surface death receptor antibody, Fas (TNF receptor superfamily member 6) antibody, FAS antibody, Fas antibody, fas antibody
    背景
    FAS is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells.Synonyms: APT1, Apo-1 antigen, FAS1, FASLG receptor, TNFRSF6, Tumor necrosis factor receptor superfamily member 6
    分子量
    37732 Da
    基因ID
    355, 9606
    UniProt
    P25445
    途径
    p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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