SULT2A1
适用: 人, 小鼠, 大鼠
WB, FACS, IHC (p), IF (cc), IF (p)
宿主: 兔
Monoclonal
3A1
unconjugated
应用备注
ELISA: 1/1,000. Western Blot: 1/100-1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
状态
Liquid
浓度
0.25 mg/mL
缓冲液
PBS with 0.09 % (W/V) Sodium Azide as preservative.
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
抗原
SULT2A1
(Sulfotransferase Family, Cytosolic, 2A, Dehydroepiandrosterone (DHEA)-Preferring, Member 1 (SULT2A1))
dhea-st antibody, dheas antibody, st2 antibody, st2a1 antibody, st2a3 antibody, sta antibody, std antibody, SULT2A1 antibody, ST2A1 antibody, Std antibody, Sth1 antibody, mSTa1 antibody, STa antibody, Smp-2 antibody, St2 antibody, St2a1 antibody, Sth2 antibody, DHEA-ST antibody, DHEAS antibody, HST antibody, ST2 antibody, ST2A3 antibody, STD antibody, hSTa antibody, sulfotransferase family 2A member 1 antibody, sulfotransferase family 2A member 1 L homeolog antibody, alcohol sulfotransferase antibody, sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 antibody, SULT2A1 antibody, sult2a1.L antibody, PCC8801_2155 antibody, Cyan8802_2217 antibody, NAL212_1203 antibody, sult2a1 antibody, Sult2a1 antibody
背景
One of the major roles of the sulfotransferases (ST) in the metabolism of drugs and endogenous compounds is the conversion of these substances into more hydrophilic water-soluble sulfate conjugates that can be easily excreted. Sulfation may also play a regulatory role for many endogenous compounds, such as steroids and neurotransmitters, by altering the biologic properties of these compounds. Otterness et al. (1992), Kong et al. (1992), and Comer et al. (1993) reported the cloning of cDNAs encoding liver dehydroepiandrosterone (DHEA) sulfotransferase. The predicted protein has 285 amino acids. Although Northern blot analysis of human liver RNA detected transcripts of 3 different sizes, Southern blot analysis of human DNA suggested that only 1 gene is present in the genome. This gene has an important role in the sulfation of both bile acids and steroids in the liver and adrenals. The human adrenal form of this enzyme is physically, immunologically, and kinetically similar, perhaps identical, to the liver form. Dehydroepiandrosterone sulfate is quantitatively one of the major steroids secreted from the adrenal cortex.Synonyms: Bile salt sulfotransferase, DHEA-ST, Dehydroepiandrosterone sulfotransferase, Hydroxysteroid Sulfotransferase, ST2A1, Sulfotransferase 2A1