Ataxin 3 抗体 (N-Term)
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Quick Overview for Ataxin 3 抗体 (N-Term) (ABIN357621)
抗原
See all Ataxin 3 (ATXN3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody is specific to Ataxin-3 (N-term).
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纯化方法
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human MJD.
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亚型
- Ig Fraction
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anti-Ataxin 3 (ATXN3) (AA 1-364) antibody
ATXN3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) antibodyATXN3 适用: 人 WB, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) (AA 1-288) antibodyATXN3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) antibodyKO Validated ATXN3 适用: 人 WB, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) (AA 261-288) antibodyATXN3 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB23951 unconjugated
anti-Ataxin 3 (ATXN3) (AA 267-297), (Middle Region) antibodyATXN3 适用: 人 WB, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) (N-Term) antibodyATXN3 适用: 人, 小鼠, 大鼠, Cow, 绵羊, 马, 兔, 豚鼠, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) (AA 120-250) antibodyATXN3 适用: 人, 小鼠, 大鼠, Cow, 绵羊, 马, 兔, 豚鼠, 犬, 猴, Pig, Cat, 小鸡, 驴, 山羊, Hamster, Avian WB 宿主: 山羊 Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) (AA 35-84) antibodyATXN3 适用: 人, 小鼠, 大鼠, Cow, 绵羊, 马, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) (AA 226-254), (C-Term) antibodyATXN3 适用: 人, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Ataxin 3 (ATXN3)
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别名
- Ataxin-3
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背景
- Machado-Joseph disease is an autosomal dominant neurologic disorder, and is now known to be the same as previously described spinocerebellar ataxia-3. MJD protein (Ataxin-3) contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is the cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. This protein interacts with key regulators (CBP, p300 and PCAF) of transcription and represses transcription, and also acts as a histone-binding protein that regulates transcription. MJD is a deubiquitinating enzyme.Synonyms: ATX3, ATXN3, MJD, MJD1, Machado-Joseph disease protein 1, SCA3, Spinocerebellar ataxia type 3 protein
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分子量
- 43450 Da
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基因ID
- 4287, 9606
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UniProt
- P54252
抗原
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