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PTP4A3 抗体

PTP4A3 适用: 人, 小鼠 WB, EIA 宿主: 小鼠 Monoclonal 111AT714 unconjugated
产品编号 ABIN356421
发货至: 中国
  • 抗原 See all PTP4A3 抗体
    PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))
    适用
    • 45
    • 23
    • 12
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 43
    • 2
    小鼠
    克隆类型
    • 44
    • 1
    单克隆
    标记
    • 23
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PTP4A3 antibody is un-conjugated
    应用范围
    • 31
    • 17
    • 10
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody is specific to PRL3.
    产品特性
    Synonyms: PRL-3, PRL-R, Protein tyrosine phosphatase type IVA 3, Protein-tyrosine phosphatase 4a3,Protein-tyrosine phosphatase of regenerating liver 3
    纯化方法
    Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    免疫原
    This monoclonal antibody is generated from mice immunized with a recombinant protein.
    克隆位点
    111AT714
    亚型
    IgG1
    Top Product
    Discover our top product PTP4A3 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blotting: 1/100-1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS containing 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))
    别名
    PRL3 / PTP4A3 (PTP4A3 产品)
    别名
    PRL-3 antibody, PRL-R antibody, PRL3 antibody, wu:fc54b05 antibody, wu:fv52d11 antibody, zgc:77109 antibody, prl-3 antibody, prl3 antibody, ptpcaax3 antibody, PTP4A3 antibody, AV088979 antibody, Prl-3 antibody, pPtp4a3 antibody, protein tyrosine phosphatase type IVA, member 3 antibody, protein tyrosine phosphatase type IVA, member 3 L homeolog antibody, protein tyrosine phosphatase 4a3 antibody, PTP4A3 antibody, ptp4a3 antibody, ptp4a3.L antibody, Ptp4a3 antibody
    背景
    PRL3 (PTP4A3) belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation.Synonyms: PRL-3, PRL-R, Protein tyrosine phosphatase type IVA 3, Protein-tyrosine phosphatase 4a3, Protein-tyrosine phosphatase of regenerating liver 3
    基因ID
    100131062
    UniProt
    O75365
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