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Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 6 (SLC17A6) 抗体

SLC17A6 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN351383
发货至: 中国
  • 抗原 See all Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 6 (SLC17A6) 抗体
    Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 6 (SLC17A6)
    适用
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    小鼠
    宿主
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    克隆类型
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    多克隆
    标记
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    非结合性
    应用范围
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    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    Specific for VGLUT2.
    交叉反应
    小鼠, 大鼠
    交叉反应 (详细)
    Other species not yet tested.
    纯化方法
    IgG
    免疫原
    A synthetic peptide from mouse VGluT2 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat.
    亚型
    IgG
    Top Product
    Discover our top product SLC17A6 Primary Antibody
  • 应用备注
    IHC, WB. A concentration of 10-50 μg,ml recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
    注意事项
    Avoid freeze and thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    有效期
    12 months
  • 抗原
    Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 6 (SLC17A6)
    别名
    VGluT2 (SLC17A6 产品)
    别名
    2900073D12Rik antibody, DNPI antibody, VGLUT2 antibody, VGluT2 antibody, Dnpi antibody, Vglut2 antibody, VGLUT2.1 antibody, blu antibody, si:packt73.2 antibody, si:packt90.2 antibody, si:xx-packt73.2 antibody, slc17a6 antibody, vglut2a antibody, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6 antibody, solute carrier family 17 member 6 antibody, solute carrier family 17 (vesicular glutamate transporter), member 6b antibody, Slc17a6 antibody, SLC17A6 antibody, slc17a6b antibody
    背景
    FUNCTION: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Membrane, Multi-pass membrane protein. Cell junction, synapse, synaptosome. TISSUE SPECIFICITY: Expressed in brain. Expressed in hippocampal neurons (at protein level). DEVELOPMENTAL STAGE: Expressed in brain throughout development. Transiently expressed in hippocampal neurons during the first week after birth, with expression decreasing thereafter. MISCELLANEOUS: Mice lacking this protein exhibit an elevated rate of perinatal lethality. Surviving animals display a strong reduction in evoked glutamergic responses in thalamic neurons. Reduction of protein level in homozygous and heterozygous knockouts leads to a graded reduction in the amplitude of the postsynaptic response to single vesicle fusion in thalamic neurons, consistent with a role for this protein in determining quantal size.,SLC17 Family,Vesicular glutamate transporter 2, VGlU2, Solute carrier family 17 member 6, Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter, Differentiation-associated BNPI, Slc17a6, Dnpi
    UniProt
    Q9JI12
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