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CD14 抗体

There is 1 publication for this product available. The 兔 多克隆 anti-CD14 antibody is suitable to detect CD14 in samples from 人. It has been validated for FACS, IP 和 Func.
产品编号 ABIN343181
发货至: 中国
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Quick Overview for CD14 抗体 (ABIN343181)

抗原

See all CD14 抗体
CD14

适用

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宿主

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克隆类型

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多克隆

标记

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This CD14 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
  • 纯化方法

    Protein G purified

    免疫原

    Affinity purified recombinant human CD14
  • 应用备注

    Suitable for Immunostaining of CD14 positive cells, Immunoprecipitation, Western blot. no significant but small inhibition of LPS binding to human CD14, Binding titre at human CD14+CHO cells (FACS) more than 1:5.000. Recommended working dilution: 1: 100 till 1.000 Binding at mouse CD14 transfected CHO+ cells more than 1:1000 (recommanded working dilution 1:10 til 1:100)

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.1 ml without NaN3

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Baveye, Elass, Fernig, Blanquart, Mazurier, Legrand: "Human lactoferrin interacts with soluble CD14 and inhibits expression of endothelial adhesion molecules, E-selectin and ICAM-1, induced by the CD14-lipopolysaccharide complex." in: Infection and immunity, Vol. 68, Issue 12, pp. 6519-25, (2000) (PubMed).

  • 抗原

    CD14

    别名

    CD14

    背景

    The antiserum represents a marker for human CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 molecule has been reported to be a receptor for endotoxin.

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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