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CD14 抗体

This anti-CD14 antibody is a 小鼠 单克隆 antibody detecting CD14 in ELISA. Suitable for 小鼠.
产品编号 ABIN343180
发货至: 中国

Quick Overview for CD14 抗体 (ABIN343180)

抗原

See all CD14 抗体
CD14

适用

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小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD14 antibody is un-conjugated

应用范围

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ELISA

克隆位点

BiG53
  • 特异性

    Membrane bound and soluble mouse CD14. The antibody blocks LPS binding to membrane bound CD14.

    纯化方法

    Protein A affinity column

    免疫原

    Monocytes of mouse

    亚型

    IgG1
  • 应用备注

    Suitable for immunostaining of CD14 positive cells and inhibition studies Binds at LPS activated mouse monocytes as well as mouse CD14 transfected cells or recombinant mouse CD14 ELISA. Inhibition of LPS binding to CD14 (Binding at LPS binding site). Up to 1 ug/ml biG53 inhibit binding of FITC-LPS (0.5ug/ml) to 6 x 105 CD14+CHO transfectants (FACS), Binding titre at mouse CD14 transfected CHO-cells: more than 20.000 (ELISA, Flow cytometry)

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute with bidistilled water

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.16

    储存液

    Without preservative

    储存条件

    -20 °C,-80 °C
  • 抗原

    CD14

    别名

    CD14

    背景

    Background: biG 53 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, weekly at surface of neutrophiles like Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 Molecule has been reported to be a receptor for endotoxin. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for LPS-LBP (lipopolysaccharide binding protein)-complexes.

    基因ID

    12475

    NCBI登录号

    NP_033971

    UniProt

    P10810

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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