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CD14 抗体

This anti-CD14 antibody is a 小鼠 单克隆 antibody detecting CD14 in ELISA. Suitable for 小鼠.
产品编号 ABIN343179
发货至: 中国

Quick Overview for CD14 抗体 (ABIN343179)

抗原

See all CD14 抗体
CD14

适用

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小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD14 antibody is un-conjugated

应用范围

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ELISA

克隆位点

BiG57
  • 特异性

    Recombinant mouse CD14. The antibody don't blocks LPS binding to membrane bound CD14.

    纯化方法

    Protein G affinity column

    免疫原

    recombinant mouse CD14

    亚型

    IgG1
  • 应用备注

    ELISA , immunostaining of mouse macrophages after stimulation 6h with LPS, Western blot with recombinant mouse CD14. Binding titre at mouse CD14 transfected CHO-cells: more than 100.000 (ELISA, Flow cytometry), no binding at LPS-binding site, endotoxin content less than 0.1ng/ml

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute with bidistilled water

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.15

    储存液

    Without preservative

    储存条件

    -20 °C,-80 °C
  • 抗原

    CD14

    别名

    CD14

    背景

    Background: biG 57 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, weekly at surface of neutrophiles like Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 Molecule has been reported to be a receptor for endotoxin. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for LPS-LBP (lipopolysaccharide binding protein)-complexes.

    分子量

    ~50kDa

    基因ID

    12475

    NCBI登录号

    NP_033971

    UniProt

    P10810

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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