LBP 抗体
(3 references)Quick Overview for LBP 抗体 (ABIN343175)
抗原
See all LBP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- Human LBP (Lipopolysaccaride binding protein). The antibody don't block LPS binding to membrane bound CD14.
-
交叉反应
- 牛, 犬, 马, 兔
-
纯化方法
- Protein A affinity column
-
免疫原
- native human LBP
-
亚型
- IgG1
-
-
anti-Lipopolysaccharide Binding Protein (LBP) (AA 226-480) antibody
LBP 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) (AA 224-468) antibodyLBP 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) (AA 25-481) antibodyLBP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) antibodyLBP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) (AA 27-481) antibodyLBP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) (AA 27-481) antibodyLBP 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) (AA 27-481) antibodyLBP 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) antibodyLBP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) antibodyLBP 适用: 小鼠 ELISA 宿主: 小鼠 Monoclonal biG35 unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) antibodyLBP 适用: 小鼠 ELISA 宿主: 小鼠 Monoclonal biG33 unconjugated
-
-
应用备注
- ELISA, Immune histology at paraffin sections, LBP inhibition studies, Western Blot. No inhibition of LPS binding to membrane bound CD14 Binding titre at human LBP- ELISA: 1:10.000
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Reconstitute with bidistilled water
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, pH 7.12
-
储存液
- Without preservative
-
储存条件
- -20 °C,-80 °C
-
-
-
: "The crystal structure of lipopolysaccharide binding protein reveals the location of a frequent mutation that impairs innate immunity." in: Immunity, Vol. 39, Issue 4, pp. 647-60, (2013) (PubMed).
: "Lipopolysaccharide-binding protein: Local expression in bovine extrahepatic tissues." in: Veterinary immunology and immunopathology, (2010) (PubMed).
: "Local expression of lipopolysaccharide-binding protein in human gingival tissues." in: Journal of periodontal research, Vol. 39, Issue 4, pp. 242-8, (2004) (PubMed).
-
: "The crystal structure of lipopolysaccharide binding protein reveals the location of a frequent mutation that impairs innate immunity." in: Immunity, Vol. 39, Issue 4, pp. 647-60, (2013) (PubMed).
-
- LBP (Lipopolysaccharide Binding Protein (LBP))
-
别名
- Lipopolysaccharide (LPS)-Binding Protein (LBP)
-
背景
- Background: Natural Lipopolysccaride Binding Protein (LBP) is a 58KD glycoprotein produced in liver. It binds at lipid A of LPS with high affinity (10-9M) and reduced the cellular LPS effects at CD14+ cells (IL1ß, IL6, TNFα). It acts as opsonin for GRAM negative cells, LPS, neutrophiles and granulocytes.
-
分子量
- ~58kDa
-
基因ID
- 3929
-
NCBI登录号
- NP_004130
-
UniProt
- P18428
-
途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process
抗原
-
