LBP 抗体
(3 references)Quick Overview for LBP 抗体 (ABIN343174)
抗原
See all LBP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Mouse LBP. The antibody don't blocks LPS binding to membrane bound CD14.
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交叉反应
- 大鼠
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纯化方法
- Protein A affinity column
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免疫原
- native mouse LBP
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亚型
- IgG2a
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anti-Lipopolysaccharide Binding Protein (LBP) (AA 226-480) antibody
LBP 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) (AA 224-468) antibodyLBP 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) (AA 25-481) antibodyLBP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) antibodyLBP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) (AA 27-481) antibodyLBP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) (AA 27-481) antibodyLBP 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) (AA 27-481) antibodyLBP 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) antibodyLBP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) antibodyLBP 适用: 人 IHC (p) 宿主: 小鼠 Monoclonal biG42 unconjugated
anti-Lipopolysaccharide Binding Protein (LBP) antibodyLBP 适用: 小鼠 ELISA 宿主: 小鼠 Monoclonal biG33 unconjugated
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应用备注
- ELISA, LBP inhibition studies, Western Blot. Non inhibition of LPS binding to membrane bound CD14, Binding titre at - ELISA: more than1:20.000
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute with bidistilled water
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.18
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储存液
- Without preservative
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储存条件
- -20 °C,-80 °C
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: "Surfactant protein a inhibits lipopolysaccharide-induced immune cell activation by preventing the interaction of lipopolysaccharide with lipopolysaccharide-binding protein." in: American journal of respiratory cell and molecular biology, Vol. 27, Issue 3, pp. 353-60, (2002) (PubMed).
: "Dual role of lipopolysaccharide (LPS)-binding protein in neutralization of LPS and enhancement of LPS-induced activation of mononuclear cells." in: Infection and immunity, Vol. 69, Issue 11, pp. 6942-50, (2001) (PubMed).
: "Binding of lipopolysaccharide (LPS) to CHO cells does not correlate with LPS-induced NF-kappaB activation." in: European journal of immunology, Vol. 30, Issue 1, pp. 211-6, (2000) (PubMed).
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: "Surfactant protein a inhibits lipopolysaccharide-induced immune cell activation by preventing the interaction of lipopolysaccharide with lipopolysaccharide-binding protein." in: American journal of respiratory cell and molecular biology, Vol. 27, Issue 3, pp. 353-60, (2002) (PubMed).
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- LBP (Lipopolysaccharide Binding Protein (LBP))
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别名
- Lipopolysaccharide (LPS)-Binding Protein (LBP)
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背景
- Background: Natural Lipopolysccaride Binding Protein (LBP) is a 58KD glycoprotein produced in liver. It binds at lipid A of LPS with high affinity (10-9M) and reduced the cellular LPS effects at CD14+ cells (IL1ß, IL6, TNFα). It acts as opsonin for GRAM negative cells, LPS, neutrophiles and granulocytes.
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分子量
- ~58kDa
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基因ID
- 16803
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UniProt
- Q61805
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process
抗原
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