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CD14 抗体 (AA 33-44)

This anti-CD14 antibody is a 小鼠 单克隆 antibody detecting CD14 in FACS 和 Agon. Suitable for 人.
产品编号 ABIN343171
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD14 抗体 (AA 33-44) (ABIN343171)

抗原

See all CD14 抗体
CD14

适用

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宿主

  • 244
  • 80
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  • 14
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  • 1
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  • 1
小鼠

克隆类型

  • 300
  • 66
  • 2
单克隆

标记

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This CD14 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Agonist (Agon)

克隆位点

BiG4
  • 抗原表位

    • 37
    • 8
    • 5
    • 5
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    • 4
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    AA 33-44

    特异性

    Soluble and membrane bound human CD14. The antibody don't block LPS binding to membrane bound CD14.

    纯化方法

    Protein A affinity column

    免疫原

    human Monocytes

    亚型

    IgG2a
  • 应用备注

    no significant inhibition of LPS binding to CD14

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute with bidistilled water

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.8

    储存液

    Without preservative

    储存条件

    -20 °C,-80 °C
  • 抗原

    CD14

    别名

    CD14

    背景

    Background: biG 4 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, weekly at surface of neutrophiles like Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 Molecule has been reported to be a receptor for endotoxin. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for LPS-LBP (lipopolysaccharide binding protein)-complexes.

    分子量

    ~50kDa

    基因ID

    929

    NCBI登录号

    NP_000582

    UniProt

    P08571

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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