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CD14 抗体 (AA 9-13, AA 39-44)

This 小鼠 单克隆 antibody specifically detects CD14 in FACS, WB, ELISA 和 Agon. It exhibits reactivity toward 人. It has been mentioned in 5+ publications
Pubmed (5 references)
产品编号 ABIN343168
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD14 抗体 (AA 9-13, AA 39-44) (ABIN343168)

抗原

See all CD14 抗体
CD14

适用

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人

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD14 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), ELISA, Agonist (Agon)

克隆位点

BiG13
Discover our top product CD14 Primary Antibody

  • 抗原表位

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    AA 9-13, AA 39-44

    特异性

    Soluble and membrane bound human CD14. The antibody blocks LPS binding to membrane bound CD14

    交叉反应

    Corynebacterium diphtheriae, 牛, 犬, 马, 猪

    交叉反应 （详细）

    CD14 of cattle++, swine ++, dog+ horse+

    纯化方法

    Protein G affinity column

    免疫原

    Monocytes of different species and immunoaffinity purified soluble human CD14

    亚型

    IgG1
  • anti-CD14 (CD14) (AA 20-214) antibody
    anti-CD14 (CD14) (AA 20-214) antibody

    CD14 适用: 人, 小鼠 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal 4B4F12 unconjugated

    anti-CD14 (CD14) (AA 20-214) antibody
    anti-CD14 (CD14) (AA 20-214) antibody

    CD14 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 1H5D8 unconjugated

    anti-CD14 (CD14) antibody
    anti-CD14 (CD14) antibody

    CD14 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 1A3B6 unconjugated

    anti-CD14 (CD14) (AA 20-345) antibody
    anti-CD14 (CD14) (AA 20-345) antibody

    CD14 适用: 人 FACS, WB, IHC, IF, ELISA 宿主: 小鼠 Monoclonal 14G1F3 unconjugated

    anti-CD14 (CD14) (AA 25-148) antibody
    anti-CD14 (CD14) (AA 25-148) antibody

    CD14 适用: 人 FACS, WB, IHC, ISt, StM 宿主: 小鼠 Monoclonal LPSR-2385 unconjugated

    anti-CD14 (CD14) (AA 230-345) antibody
    anti-CD14 (CD14) (AA 230-345) antibody

    CD14 适用: 人 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal 1D1F8 unconjugated

    anti-CD14 (CD14) (AA 54-83), (N-Term) antibody
    anti-CD14 (CD14) (AA 54-83), (N-Term) antibody

    CD14 适用: 人 FACS, WB, IF, IHC (p) 宿主: 兔 Polyclonal RB14105 unconjugated

    anti-CD14 (CD14) (AA 201-300) antibody
    anti-CD14 (CD14) (AA 201-300) antibody

    CD14 适用: 人, 小鼠, 大鼠, 绵羊, 犬, 兔 WB, ELISA, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

    anti-CD14 (CD14) (Internal Region) antibody
    anti-CD14 (CD14) (Internal Region) antibody

    Verified CD14 适用: 人 FACS, WB, ELISA 宿主: 山羊 Polyclonal unconjugated

    anti-CD14 (CD14) (AA 25-148) antibody
    anti-CD14 (CD14) (AA 25-148) antibody

    CD14 适用: 人 WB, IHC, ISt, StM 宿主: 小鼠 Monoclonal LPSR-2397 unconjugated

  • 应用备注

    20 μg/mL inhibits binding of 0.5 μg/ ml LPS to CD14.Binding titre at human CD14 transfected CHO-cells (FACS): more than 100.000.

    限制

    仅限研究用

  • 状态

    Lyophilized

    溶解方式

    Reconstitute with bidistilled water

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.5

    储存液

    Without preservative

    储存条件

    -20 °C,-80 °C
  • Moyo, Marchi, Steinbach: "Differentiation and activation of equine monocyte-derived dendritic cells are not correlated with CD206 or CD83 expression." in: Immunology, Vol. 139, Issue 4, pp. 472-83, (2013) (PubMed).

    Bache, Spreitzer, Becker, Loeschner, Rosskopf, Hanschmann, Schwanig, Schneider, Lieb, Montag: "Bordetella Pertussis Toxin does not induce the release of pro-inflammatory cytokines in human whole blood." in: Medical microbiology and immunology, Vol. 201, Issue 3, pp. 327-35, (2012) (PubMed).

    Kato, Ogasawara, Homma, Saito, Matsumoto: "Lipopolysaccharide-binding protein critically regulates lipopolysaccharide-induced IFN-beta signaling pathway in human monocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 10, pp. 6185-94, (2004) (PubMed).

    Berner, Fürll, Stelter, Dröse, Müller, Schütt: "Elevated levels of lipopolysaccharide-binding protein and soluble CD14 in plasma in neonatal early-onset sepsis." in: Clinical and diagnostic laboratory immunology, Vol. 9, Issue 2, pp. 440-5, (2002) (PubMed).

    Vidal, Labéta, Schiffrin, Donnet-Hughes: "Soluble CD14 in human breast milk and its role in innate immune responses." in: Acta odontologica Scandinavica, Vol. 59, Issue 5, pp. 330-4, (2001) (PubMed).

  • 抗原

    CD14

    别名

    CD14

    背景

    Background: biG 13 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, weekly at surface of neutrophiles like Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 Molecule has been reported to be a receptor for endotoxin. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for LPS-LBP (lipopolysaccharide binding protein)-complexes.

    分子量

    ~50kDa

    基因ID

    929

    NCBI登录号

    NP_000582

    UniProt

    P08571

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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