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CD14 抗体 (N-Term)

This anti-CD14 antibody is a 小鼠 单克隆 antibody detecting CD14 in FACS, IP 和 IHC (fro). Suitable for 人 和 猴.
产品编号 ABIN319685
发货至: 中国

Quick Overview for CD14 抗体 (N-Term) (ABIN319685)

抗原

See all CD14 抗体
CD14

适用

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人, 猴

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD14 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

UCHM1
  • 抗原表位

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    AA 1-4, N-Term

    纯化方法

    Affinity chromatography on Protein G

    免疫原

    Human Thymocytes followed by peripheral blood mononuclear cells. Spleen cells from mice immunised with human thymocytes and PBLs were fused with cells from the NS1-Ag4/1 mouse myeloma cell line.

    亚型

    IgG2a
  • 应用备注

    Flow cytometry. Immunhistology on frozen sections. Recommended Positive Control: Tonsil. Immunprecipitation.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CD14

    别名

    CD14

    背景

    CD14 is a single copy gene encoding 2 protein forms: a 50 to 55 kDa glycosylphosphatidylinositol anchored membrane protein (mCD14) and a monocyte or liver derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS) dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram negative shock. CD14 also appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein

    基因ID

    9606

    UniProt

    P08571

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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