ATR 抗体 (Ser428)
This anti-ATR antibody is a 兔 多克隆 antibody detecting ATR in IHC (p). Suitable for 人.
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Quick Overview for ATR 抗体 (Ser428) (ABIN319379)
抗原
See all ATR 抗体
ATR
(Ataxia Telangiectasia and Rad3 Related (ATR))
适用
人
宿主
兔
克隆类型
多克隆
标记
This ATR antibody is un-conjugated
应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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抗原表位
- Ser428
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特异性
- This antibody detects endogenous levels of total ATR protein.
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纯化方法
- Immunoaffinity Chromatography.
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免疫原
- The antiserum was produced against synthesized non-phosphopeptide derived from human ATR around the phosphorylation site of Serine 428 (G-I-SP-P-K).
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anti-Ataxia Telangiectasia and Rad3 Related (ATR) (AA 2353-2644) antibody
ATR 适用: 人 WB, IP, ICC, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ataxia Telangiectasia and Rad3 Related (ATR) (Internal Region) antibodyATR 适用: 人, 小鼠, 犬, 鱼, 猴, 大鼠, 非洲爪蟾 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (1/50-1/100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at-20 °C.
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- ATR (Ataxia Telangiectasia and Rad3 Related (ATR))
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别名
- ATR / FRP1
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背景
- Ataxia Telangiectasia Mutated (ATM) and Rad 3-related protein (ATR) is a phosphatidylinositol kinase (PK)-related kinase which functions in response to DNA damage and repair as well as at DNA replication checkpoints during the cell cycle. ATR is a member of the DNA-PK kinases closely related to ATM and DNA-PK for which DNA stimulates the observed kinase activity. Chromosomal remodeling proteins have also been reported to associate with ATR complexes. Several known components of the NuRD complex including histone deacetylase 1 (HDAC1), HDAC2, and CHD4.Synonyms: Ataxia telangiectasia and Rad3-related protein, FRAP-related protein 1, Serine/threonine-protein kinase ATR
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基因ID
- 545
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NCBI登录号
- NP_001175
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UniProt
- Q13535
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途径
- p53 Pathway, Apoptosis, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
抗原
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