电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Phospholipase C gamma 2 抗体 (pTyr1217)

This anti-Phospholipase C gamma 2 antibody is a 兔 多克隆 antibody detecting Phospholipase C gamma 2 in IHC (p). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN319284
发货至: 中国

Quick Overview for Phospholipase C gamma 2 抗体 (pTyr1217) (ABIN319284)

抗原

See all Phospholipase C gamma 2 (PLCG2) 抗体
Phospholipase C gamma 2 (PLCG2)

适用

  • 116
  • 54
  • 40
  • 6
  • 4
  • 4
  • 4
  • 4
  • 3
  • 1
人, 大鼠, 小鼠

宿主

  • 109
  • 7

克隆类型

  • 109
  • 7
多克隆

标记

  • 55
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This Phospholipase C gamma 2 antibody is un-conjugated

应用范围

  • 91
  • 40
  • 40
  • 33
  • 31
  • 23
  • 16
  • 15
  • 11
  • 8
  • 7
  • 2
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 28
    • 16
    • 16
    • 13
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr1217

    特异性

    This antibody detects endogenous levels of PLC-gamma 2 only when phosphorylated at Tyrosine 1217.

    纯化方法

    Immunoaffinity Chromatography: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

    免疫原

    The antiserum was produced against synthesized phosphopeptide derived from Human PLC-gamma 2 around the phosphorylation site of Tyrosine 1217 (F-L-Yp-D-T).
  • 应用备注

    Immunohistochemistry (1/50-1/100).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at-20 °C.
  • 抗原

    Phospholipase C gamma 2 (PLCG2)

    别名

    PLCG2

    背景

    Enzymes of the phospholipase C family catalyze the hydrolysis of phospholipids to yield diacylglycerols and water soluble phosphorylated derivatives of the lipid head groups. A number of these enzymes have specificity for phosphoinositides. Of the phosphoinositide specific phospholipase C enzymes, C beta is regulated by heterotrimeric G protein coupled receptors, while the closely related C gamma 1 and C gamma 2 enzymes are controlled by receptor tyrosine kinases. The C gamma 1 and C gamma 2 enzymes are composed of phospholipase domains that flank regions of homology to noncatalytic domains of the SRC oncogene product, SH2 and SH3.Synonyms: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma-2, PLC-IV, PLC-gamma-2, Phosphoinositide phospholipase C-gamma-2, Phospholipase C-IV, Phospholipase C-gamma-2

    基因ID

    5336

    NCBI登录号

    NP_002652

    UniProt

    P16885

    途径

    RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
You are here:
Chat with us!