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Connexin 43/GJA1 抗体 (pSer368)

GJA1 适用: 人, 大鼠, 小鼠, 犬, Cow, 小鸡, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN319138
发货至: 中国
  • 抗原 See all Connexin 43/GJA1 (GJA1) 抗体
    Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
    抗原表位
    • 21
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    pSer368
    适用
    • 134
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    人, 大鼠, 小鼠, 犬, Cow, 小鸡, 豚鼠, 斑马鱼
    宿主
    • 129
    • 8
    • 4
    • 1
    克隆类型
    • 133
    • 8
    多克隆
    标记
    • 82
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    This Connexin 43/GJA1 antibody is un-conjugated
    应用范围
    • 97
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    Western Blotting (WB)
    特异性
    This antibody specifically recognises 43 kDa Connexin43, when phosphorylated at Ser368.
    纯化方法
    Affinity chromatography
    免疫原
    Synthetic phosphopeptide corresponding to an amino acid sequence within connexin43 which includes phosphorylated Ser368
    亚型
    IgG
    Top Product
    Discover our top product GJA1 Primary Antibody
  • 应用备注
    Western Blot: 1: 1000, detects a band of approximately 43 kDa in rat hippocampus celllysates.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    10 mM HEPES, pH 7.5 containing 0.09 % Sodium Azide, 0.01 % Bovine Serum Albumin, 50 % Glycerol
    储存液
    Sodium azide
    注意事项
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
    别名
    GJA1 / Cx43 (GJA1 产品)
    别名
    AVSD3 antibody, CX43 antibody, DFNB38 antibody, GJAL antibody, HLHS1 antibody, HSS antibody, ODDD antibody, Cx43 antibody, AU042049 antibody, AW546267 antibody, Cnx43 antibody, Cx43alpha1 antibody, Gja-1 antibody, Npm1 antibody, connexin43 antibody, cx43a1 antibody, gja1 antibody, zfCx43.3 antibody, connexin 43 antibody, gja1-A antibody, cx43 antibody, gjal antibody, oddd antibody, dfnb38 antibody, gap junction protein alpha 1 antibody, gap junction protein, alpha 1 antibody, connexin 43 antibody, gap junction protein alpha 1 L homeolog antibody, CONNEXIN 43 protein antibody, GJA1 antibody, Gja1 antibody, cx43 antibody, gja1.L antibody, gja1 antibody, CONNEXIN 43 antibody
    背景
    Connexin43 (CX43) allows for the exchange of solutions between neighbouring cells through the formation of gap-junctional channels and is expressed in the brain, kidneys and myocardium, as well as vascular endothelial cells. Studies suggest that a decrease in the permeability of gap-junctional channels occurs due to a conformational change in the structure of CX43, and that this is mediated by the phosphorylation of CX43 at residue Ser368, by Protein Kinase C (PKC). A possible link between CX43 and epilepsy has been investigated following the detection of high levels of CX43 in both low-grade tumours and peritumoural reactive astrocytes (3).Synonyms: Connexin-43, GJAL, Gap junction 43 kDa heart protein, Gap junction alpha-1 protein
    基因ID
    2697
    NCBI登录号
    NP_000156
    UniProt
    P17302
    途径
    MAPK Pathway, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
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