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FAIM3 抗体 (C-Term)

FAIM3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN318759
发货至: 中国
  • 抗原 See all FAIM3 抗体
    FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))
    抗原表位
    • 15
    • 6
    • 4
    • 3
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    • 1
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    C-Term
    适用
    • 29
    • 9
    • 3
    宿主
    • 30
    • 5
    克隆类型
    • 33
    • 2
    多克隆
    标记
    • 17
    • 3
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    • 2
    • 1
    • 1
    • 1
    • 1
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    This FAIM3 antibody is un-conjugated
    应用范围
    • 30
    • 14
    • 14
    • 13
    • 6
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    • 1
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    Western Blotting (WB)
    特异性
    This antibody detects an epitope within the C-terminal (CT) region of Human Toso, also known as Fas Apoptotic Inhibitory Molecule 3 (FAIM3). In Western Bloting, This antibody detects a band of approximately 43 kDa in Human lung tissue lysate.
    交叉反应 (详细)
    Species reactivity (expected):Rat and Mouse.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography
    免疫原
    A 13 amino acid peptide from near the carboxy terminus of Human Toso. Genename: TOSO
    亚型
    IgG
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  • 应用备注
    Western Blot: 1 - 2g/mL, detects a band of approximately 43 kDa in human lung tissuelysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS, 0.02 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))
    别名
    FAIM3 / TOSO (FAIM3 产品)
    别名
    FAIM3 antibody, FCMR antibody, TOSO antibody, 1810037B05Rik antibody, FcmuR antibody, Toso antibody, Fc fragment of IgM receptor antibody, FCMR antibody, Fcmr antibody
    背景
    Toso is expressed by lymphoid and haematopoietic cells and is up-regulated by T-cell activation. Toso expressing cells have increased resistance to Fas-, FADD-, and TNFalpha-induced apoptosis. Toso is membrane bound, and is thought to directly bind to FADD, disrupting DISC formation and thus inhibiting caspase-8 activation. Toso is a potential proto-oncogene, and could be a therapeutic target for use in the treatment of autoimmune diseases. Despite its predicted molecular weight, Toso often migrates at 60 kDa in SDS PAGE.Synonyms: Fas apoptotic inhibitory molecule 3, Regulator of Fas-induced apoptosis Toso
    基因ID
    9214
    NCBI登录号
    NP_001135945
    UniProt
    O60667
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