MAP2K4 抗体 (pSer80)
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北京 101111
Quick Overview for MAP2K4 抗体 (pSer80) (ABIN318113)
抗原
See all MAP2K4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer80
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特异性
- This antibody detects endogenous levels of SEK1/MKK4 pSer80 protein.
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) antibody
MAP2K4 适用: 人 WB, IHC, IF, IHC (p), IP, FACS 宿主: 小鼠 Monoclonal 4B4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) antibodyMAP2K4 适用: 人 WB, IHC, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 1D6 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) antibodyMAP2K4 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 2E4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) (AA 137-394) antibodyMAP2K4 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) antibodyMAP2K4 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5H4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) (AA 1-399) antibodyMAP2K4 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) (AA 259-398) antibodyMAP2K4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) (pSer80) antibodyMAP2K4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) (pSer257), (pThr261) antibodyMAP2K4 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) (pThr261) antibodyMAP2K4 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))
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别名
- MAP2K4
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背景
- A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK-5, whereas MEK-6 phosphorylates p38 and p38β. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.Synonyms: Dual specificity mitogen-activated protein kinase kinase 4, JNK-activating kinase 1, MAP Kinase Kinase 4, MAPKK4, MEK-4, MKK4, PRKMK4, SAPK/ERK kinase 1, SERK1, c-Jun N-terminal kinase kinase 1
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分子量
- approx. 44 kDa
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基因ID
- 6416
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NCBI登录号
- NP_003001
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UniProt
- P45985
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途径
- MAPK Pathway, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling
抗原
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