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ATF2 抗体 (pThr53, pThr71)

The 兔 多克隆 anti-ATF2 antibody is suitable to detect ATF2 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IP 和 IHC (p).
产品编号 ABIN317966
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ATF2 抗体 (pThr53, pThr71) (ABIN317966)

抗原

See all ATF2 抗体
ATF2 (Activating Transcription Factor 2 (ATF2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ATF2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    pThr53, pThr71

    特异性

    P-ATF2 (pThr71/53) antibody detects endogenous levels of p-ATF2 protein.

    纯化方法

    Affinity chromatography
  • 应用备注

    ELISA: 1: 20000approx. 1: 40000. Western Blot: 1: 500approx. 1: 1000. Immunohistochemistry: 1: 50approx. 1: 200. Immunoprecipitation: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    ATF2 (Activating Transcription Factor 2 (ATF2))

    别名

    ATF2

    背景

    Eukaryotic gene transcription is regulated by sequence-specific transcription factors which bind modular CIS acting promotor and enhancer elements. The cAMP response element (CRE), one of the best studied of such elements, consists of the palindromic octanucleotide TGACGTCA. Several CRE binding proteins have been identified within the ATF/CREB family, the best characterized of which include CREB-1, CREB-2 (also designated ATF-4), ATF-1, ATF-2 and ATF-3. These proteins share highly related COOH terminal leucine zipper dimerization and basic DNA binding domains but are highly divergent in their amino terminal domains. Although each of the ATF/CREB proteins appear capable of binding CRE in its homodimeric form, certain of these also bind as heterodimers, both within the ATF/CREB family and even with members of the AP-1 transcription factor family.Synonyms: ATF-2, Activating transcription factor 2, CRE-BP1, CREB-2, CREB2, CREBP1, Cyclic AMP-dependent transcription factor ATF-2, Cyclic AMP-responsive element-binding protein 2, HB16, cAMP response element-binding protein CRE-BP1, cAMP-dependent transcription factor ATF-2

    基因ID

    1386

    NCBI登录号

    NP_001871

    UniProt

    P15336

    途径

    MAPK Pathway, RTK signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
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