ATF2 抗体 (pThr53, pThr71)
Our Local Distributor
北京 101111
Quick Overview for ATF2 抗体 (pThr53, pThr71) (ABIN317966)
抗原
See all ATF2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pThr53, pThr71
-
特异性
- P-ATF2 (pThr71/53) antibody detects endogenous levels of p-ATF2 protein.
-
纯化方法
- Affinity chromatography
-
-
-
-
应用备注
-
ELISA: 1: 20000approx. 1: 40000. Western Blot: 1: 500approx. 1: 1000. Immunohistochemistry: 1: 50approx. 1: 200. Immunoprecipitation: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1,0 mg/mL
-
缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- ATF2 (Activating Transcription Factor 2 (ATF2))
-
别名
- ATF2
-
背景
- Eukaryotic gene transcription is regulated by sequence-specific transcription factors which bind modular CIS acting promotor and enhancer elements. The cAMP response element (CRE), one of the best studied of such elements, consists of the palindromic octanucleotide TGACGTCA. Several CRE binding proteins have been identified within the ATF/CREB family, the best characterized of which include CREB-1, CREB-2 (also designated ATF-4), ATF-1, ATF-2 and ATF-3. These proteins share highly related COOH terminal leucine zipper dimerization and basic DNA binding domains but are highly divergent in their amino terminal domains. Although each of the ATF/CREB proteins appear capable of binding CRE in its homodimeric form, certain of these also bind as heterodimers, both within the ATF/CREB family and even with members of the AP-1 transcription factor family.Synonyms: ATF-2, Activating transcription factor 2, CRE-BP1, CREB-2, CREB2, CREBP1, Cyclic AMP-dependent transcription factor ATF-2, Cyclic AMP-responsive element-binding protein 2, HB16, cAMP response element-binding protein CRE-BP1, cAMP-dependent transcription factor ATF-2
-
基因ID
- 1386
-
NCBI登录号
- NP_001871
-
UniProt
- P15336
-
途径
- MAPK Pathway, RTK signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
抗原
-