SPTBN1 抗体
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- 抗原 See all SPTBN1 抗体
- SPTBN1 (Spectrin Beta, Non-Erythrocytic 1 (SPTBN1))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SPTBN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Spectrin β II antibody detects endogenous levels of Spectrin β II protein.(region surrounding Met687)
- 纯化方法
- Affinity chromatography
- Top Product
- Discover our top product SPTBN1 Primary Antibody
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anti-Spectrin Beta, Non-Erythrocytic 1 (SPTBN1) (AA 2096-2256) antibody
SPTBN1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Spectrin Beta, Non-Erythrocytic 1 (SPTBN1) (N-Term) antibodySPTBN1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Spectrin Beta, Non-Erythrocytic 1 (SPTBN1) (AA 2063-2097) antibodySPTBN1 适用: 小鼠 WB 宿主: 兔 Polyclonal RB54579 unconjugated
anti-Spectrin Beta, Non-Erythrocytic 1 (SPTBN1) antibodySPTBN1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Spectrin Beta, Non-Erythrocytic 1 (SPTBN1) (AA 2100-2200) antibodySPTBN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- SPTBN1 (Spectrin Beta, Non-Erythrocytic 1 (SPTBN1))
- Abstract
- SPTBN1 产品
- 别名
- 9930031C03Rik antibody, AL033301 antibody, SPTB2 antibody, Spnb-2 antibody, Spnb2 antibody, elf1 antibody, elf3 antibody, mKIAA4049 antibody, ELF antibody, betaSpII antibody, Spnb1 antibody, spectrin beta, non-erythrocytic 1 antibody, spectrin, beta, non-erythrocytic 1 antibody, Sptbn1 antibody, SPTBN1 antibody
- 背景
- Spectrin is an actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Spectrin α I and spectrin β I are present in erythrocytes, whereas spectrin α II (also designated fodrin α) and spectrin β II (also designated fodrin β) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Defects in the SPTB gene encoding spectrin β I are the cause of spherocytosis type I (SPH1), a disorder characterized by severe hemolytic anemia. Another disorder due to defects of SPTB is called elliptocytosis or elliptocytosis 3 (EL3). The human SPTB gene maps to chromosome 14q22-q23.2 and encodes the 2,137 amino acid, 246 kDa erythroid form of β-spectrin.Synonyms: Beta-II spectrin, Fodrin beta chain, SPTB2, Spectrin beta chain brain 1, Spectrin non-erythroid beta chain 1
- 分子量
- approx. 275 kDa
- 基因ID
- 6711
- NCBI登录号
- NP_003119
- UniProt
- Q01082
- 途径
- Regulation of Actin Filament Polymerization, Protein targeting to Nucleus
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