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DCT 抗体

DCT 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317917
发货至: 中国
  • 抗原 See all DCT 抗体
    DCT (Dopachrome Tautomerase (DCT))
    适用
    • 81
    • 24
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 80
    • 1
    克隆类型
    • 80
    • 1
    多克隆
    标记
    • 40
    • 8
    • 8
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DCT antibody is un-conjugated
    应用范围
    • 69
    • 51
    • 23
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    TRP2 antibody detects endogenous levels of TRP2 protein.(region surrounding Lys89)
    纯化方法
    Affinity chromatography
    Top Product
    Discover our top product DCT Primary Antibody
  • 应用备注
    ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    DCT (Dopachrome Tautomerase (DCT))
    别名
    TYRP2 / DCT (DCT 产品)
    别名
    TYRP2 antibody, RGD1564975 antibody, trp2 antibody, DT antibody, TRP-2 antibody, TRP2 antibody, Tyrp-2 antibody, Tyrp2 antibody, slaty antibody, slt antibody, zgc:109860 antibody, dopachrome tautomerase antibody, dopachrome tautomerase L homeolog antibody, DCT antibody, Dct antibody, dct antibody, dct.L antibody
    背景
    Tyrosinase (TYR), a type I membrane protein and copper-containing enzyme,is involved in the production of melanin, the primary pigment found in vertebrates.Melanin biogenesis requires the enzymatic activity of TYR, which catalyzes the critical and rate-limiting step of tyrosine hydroxylation in the biosynthesis of melanin. Defects effecting TYR activity result in various forms of albinism. The TYR-related proteins, TRP1 and TRP2, are also specifically expressed in melanocytes, and they likewise contribute to the synthesis of melanin within the melanosomes. The TRPs, including TYR, all share a similar transmembrane region, contain two metal-binding regions and a cysteinerich epidermal growth factor motif, and are localized in the melanosomal membrane. These proteins, however, have distinct catalytic activity, and they individually contribute to the biosynthesis of melanin biopolymers. The TRPs are believed to exist as a multi-enzyme complex, as these proteins form aggregates together, and the expression of TRP1 also helps stabilize TYR in melanocytes.Synonyms: L-dopachrome Delta-isomerase, L-dopachrome tautomerase, TRP-2, TRP2, Tyrosinase-related protein 2
    分子量
    approx. 60 kDa
    基因ID
    1638
    NCBI登录号
    NP_001913
    UniProt
    P40126
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