GNL1 抗体
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- 抗原 See all GNL1 抗体
- GNL1 (Guanine Nucleotide Binding Protein Like Protein 1 (GNL1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GNL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- GNL1 antibody detects endogenous levels of GNL1 protein.(region surrounding Gln103)
- 纯化方法
- Affinity chromatography
- Top Product
- Discover our top product GNL1 Primary Antibody
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anti-Guanine Nucleotide Binding Protein Like Protein 1 (GNL1) (N-Term) antibody
GNL1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein Like Protein 1 (GNL1) (AA 251-500) antibodyGNL1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein Like Protein 1 (GNL1) (N-Term) antibodyGNL1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein Like Protein 1 (GNL1) (AA 1-607) antibodyGNL1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein Like Protein 1 (GNL1) antibodyGNL1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein Like Protein 1 (GNL1) (AA 83-375) antibodyGNL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein Like Protein 1 (GNL1) (AA 1-180) antibodyGNL1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- GNL1 (Guanine Nucleotide Binding Protein Like Protein 1 (GNL1))
- 别名
- GNL1 / HSR1 (GNL1 产品)
- 别名
- HSR1 antibody, Gna-rs1 antibody, Gnal1 antibody, G protein nucleolar 1 (putative) antibody, guanine nucleotide binding protein-like 1 antibody, G protein nucleolar 1 antibody, GNL1 antibody, Gnl1 antibody
- 背景
- GNL1 (guanine nucleotide-binding protein-like 1) is a nuclear protein that likely acts as a regulator of the histocompatibility cluster. GNL1 and MMR1, the murine homolog, are localized within or close to the MHC class I region and belong to the MMR1/HSR1 GTP-binding protein family. GTPases, such as GNL1, from the MMR1/HSR1 GTP-binding protein subfamily are circularly rearranged G-motifs that play a critical role in maintaining normal cell growth. Deletion of these genes results in severe growth defects with a marked reduction in mature rRNA species and a concomitant accumulation of the 35S pre-rRNA transcript. Deletion also causes the ribosomal protein RPL25A to fail exportation from the nucleolus. Deletion of any of the G-domain motifs will result in a null phenotype and nuclear/nucleolar localization that lacks the nucleolar export of preribosomes and is accompanied by a distortion of the nucleolar structure. Upon DNA damage GNL1 is phosphorylated by a kinase, possibly Atm or ATR.Synonyms: GTP-binding protein HSR1, Guanine nucleotide-binding protein-like 1
- 分子量
- approx. 69 kDa
- 基因ID
- 2794
- NCBI登录号
- NP_005266
- UniProt
- P36915
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